Varshochi Mojtaba, Kianmehr Parisa, Naghavi-Behzad Mohammad, Bayat-Makoo Zhinous
Infectious and Tropical Diseases Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran.
Infez Med. 2013 Jun;21(2):103-10.
Pneumonia severity assessment systems, such as the pneumonia severity index (PSI) and CURB-65, were designed to guide physicians to admit the patients involved to appropriate wards of hospitals. This study evaluated concordance rate of decisions leading to patients' hospitalization in accordance with PSI and CURB-65 criteria and comparison of the two systems' P-values in evaluating mortality and the hospitalization period of the patients in question. A total of 134 hospitalized patients with community-acquired pneumonia (CAP) were evaluated. Patients were classified on the basis of risk factors implicated in the PSI and CURB-65 systems. Prognostic P-values and indication measures of hospitalization for the two systems were then compared. Eighty-seven males (64.9%) and 47 females (35.1%) with a mean age of 64.23±19.82 (15-103) years were enrolled in the study. Based on the results of both systems, hospitalization was indicated in 112 cases (83.6%) and there was total agreement between the two systems in 61 cases (45.5%). There was no significant association between hospitalization duration in the two systems. However, both systems significantly predicted mortality within the hospitalization period with rather equal accuracies. Patients expired more frequently in the group with indication of hospitalization based on the PSI classes. However, there was no significant difference in the mortality between the two groups with and without admission indication according to the CURB-65 system. A considerable portion of our hospitalizations met the related criteria of the PSI/CURB-65. The two evaluation systems have near equal sensitivity and specificity for predicting mortality among hospitalized patients with CAP when the PSI class IV-V and CURB-65 score ≥ 2.
肺炎严重程度评估系统,如肺炎严重指数(PSI)和CURB-65,旨在指导医生将相关患者收治到医院的合适病房。本研究评估了根据PSI和CURB-65标准做出的患者住院决策的符合率,以及这两种系统在评估相关患者死亡率和住院时间方面P值的比较。共评估了134例住院的社区获得性肺炎(CAP)患者。根据PSI和CURB-65系统中涉及的风险因素对患者进行分类。然后比较这两种系统的预后P值和住院指征指标。本研究纳入了87例男性(64.9%)和47例女性(35.1%),平均年龄为64.23±19.82(15 - 103)岁。根据两种系统的结果,112例(83.6%)患者需要住院治疗,两种系统完全一致的情况有61例(45.5%)。两种系统的住院时长之间无显著关联。然而,两种系统都能以相当的准确性显著预测住院期间的死亡率。基于PSI分级有住院指征的组中患者死亡更频繁。然而,根据CURB-65系统,有住院指征和无住院指征的两组之间死亡率无显著差异。我们相当一部分住院病例符合PSI/CURB-65的相关标准。当PSI为IV - V级且CURB-65评分≥2时,这两种评估系统在预测CAP住院患者死亡率方面具有近乎相同的敏感性和特异性。