Antoci Eugenio, Pinzone Marilia Rita, Nunnari Giuseppe, Stefani Stefania, Cacopardo Bruno
Department of Clinical and Molecular Biomedicine, Division of Infectious Diseases, University of Catania, Italy.
Infez Med. 2013 Jun;21(2):125-9.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare-associated infections worldwide and has recently been identified as an emerging pathogen in livestock and companion animals. Livestock-associated MRSA (LA-MRSA) may be responsible for increased rates of colonization and/or infection among people working on farms. We evaluated the prevalence and molecular characteristics of MRSA among dairy farmers in the province of Ragusa, South-Eastern Sicily, their animals and bulk tank milk samples. A surprisingly high number of samples tested positive for MRSA: 36% of human nasal swabs, 61% of bovine nasal swabs and 44% of bulk tank milk samples. MRSA carrier prevalence in humans significantly correlated with the percentage of positive cows on the farm, the number of livestock units and the presence of consensual positive bulk tank milk samples. Prospective studies are needed to investigate MRSA transmission between animals and humans and implement preventive strategies.
耐甲氧西林金黄色葡萄球菌（MRSA）是全球医疗保健相关感染的主要原因，最近被确定为家畜和伴侣动物中的一种新兴病原体。与家畜相关的MRSA（LA-MRSA）可能是导致农场工作人员定植率和/或感染率增加的原因。我们评估了西西里岛东南部拉古萨省奶农、他们的动物以及散装奶罐奶样中MRSA的流行情况和分子特征。令人惊讶的是，大量样本的MRSA检测呈阳性：36%的人类鼻拭子、61%的牛鼻拭子和44%的散装奶罐奶样。人类中MRSA携带者的流行率与农场中阳性奶牛的百分比、牲畜单位数量以及散装奶罐奶样一致呈阳性的情况显著相关。需要进行前瞻性研究来调查动物与人类之间的MRSA传播并实施预防策略。
