Ge Yipeng, Sun Lizhong, Zhu Junming, Liu Yongmin, Cheng Lijian, Chen Lei, Zheng Jun, Li Chengnan, Liu Wei
Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Thorac Cardiovasc Surg. 2013 Oct;61(7):564-8. doi: 10.1055/s-0033-1348197. Epub 2013 Jun 17.
EuroSCORE is a widely used objective risk scoring model.
The aim of this study was to evaluate the validation of EuroSCORE II for predicting in-hospital mortality and length of intensive care unit (ICU) stay after total aortic arch replacement with stented elephant trunk implantation for DeBakey Type I aortic dissection.
Between February 2009 and February 2012, data from 384 consecutive patients, who underwent aortic surgery using total aortic arch replacement with stented elephant trunk implantation, were collected retrospectively. EuroSCORE II was applied to predict mortality and length of ICU stay. The C-statistic was used to test discrimination of the model. Calibration was assessed with the Hosmer-Lemeshow goodness-of-fit statistic.
The in-hospital mortality was 8.07%. The mean length of ICU stay was 3.06 days. A total of 75 patients remained at ICU for 5 days or more and 42 patients for 7 days or more. EuroSCORE II did not show good discriminatory ability in predicting mortality and length of ICU stay. The C-statistic of predicting mortality, ICU stay for 5 days or more, and ICU stay for 7 days or more were 0.49, 0.56, and 0.52, respectively. The calibration was poor for predicting mortality (p < 0.001), ICU stay for 5 days or more (p < 0.001), and ICU stay for 7 days or more (p < 0.001).
Although EuroSCORE II is the newest risk model for cardiac surgery, it is not accurate when it is applied for thoracic aortic surgery. A new risk evaluating system specially designed for aortic surgery should be developed in the future.
欧洲心脏手术风险评估系统(EuroSCORE)是一种广泛使用的客观风险评分模型。
本研究旨在评估欧洲心脏手术风险评估系统II(EuroSCORE II)在预测Debakey I型主动脉夹层带支架象鼻植入术全主动脉弓置换术后院内死亡率和重症监护病房(ICU)住院时间方面的有效性。
回顾性收集2009年2月至2012年2月期间384例连续接受带支架象鼻植入术全主动脉弓置换术的主动脉手术患者的数据。应用EuroSCORE II预测死亡率和ICU住院时间。采用C统计量检验模型的辨别能力。用Hosmer-Lemeshow拟合优度统计量评估校准情况。
院内死亡率为8.07%。ICU平均住院时间为3.06天。共有75例患者在ICU停留5天或更长时间,42例患者停留7天或更长时间。EuroSCORE II在预测死亡率和ICU住院时间方面未显示出良好的辨别能力。预测死亡率、ICU停留5天或更长时间以及ICU停留7天或更长时间的C统计量分别为0.49、0.56和0.52。预测死亡率(p<0.001)、ICU停留5天或更长时间(p<0.001)以及ICU停留7天或更长时间(p<0.001)时校准效果较差。
尽管EuroSCORE II是心脏手术最新的风险模型,但应用于胸主动脉手术时并不准确。未来应开发专门针对主动脉手术的新风险评估系统。