Palazzuoli V, Martini G, Giovani S, Mondillo S, Giusti R, D'Arpino A, Ricci D
Istituto di Clinica medica generale e Terapia medica, Università, Siena.
Recenti Prog Med. 1990 Apr;81(4):263-5.
The authors report the clinical history of a 56-year-old man with cardiomyopathy due to undiagnosed hypocalcemia. Heart dilation and hypokinesia were assessed by echocardiography. Cardiac failure was refractory to digitalis preparations and to diuretics. The restoration of serum calcium to normal levels obtained with adequate therapy dramatically improved the motion of ventricular walls and decreased the size of the left ventricle. The pathogenetic mechanisms of hypocalcemic cardiomyopathy are discussed and the importance of considering the possibility of hypocalcemia when dealing with the differential diagnosis of cardiomyopathies is underlined. In the presence of hypocalcemic cardiomyopathy, the correction of calcium deficiency with calcitriol is the treatment of choice.
作者报告了一名56岁男性因未确诊的低钙血症导致心肌病的临床病史。通过超声心动图评估心脏扩张和运动减弱情况。心力衰竭对洋地黄制剂和利尿剂均无效。通过适当治疗使血清钙恢复至正常水平后,心室壁运动显著改善,左心室大小减小。文中讨论了低钙血症性心肌病的发病机制,并强调在心肌病鉴别诊断时考虑低钙血症可能性的重要性。对于低钙血症性心肌病,选择骨化三醇纠正钙缺乏作为治疗方法。