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从拉萨大黄(Rheum lhasaense)的根部提取到新的白藜芦醇低聚物衍生物。

New resveratrol oligomer derivatives from the roots of Rheum lhasaense.

机构信息

Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650031, Yunnan, China.

出版信息

Molecules. 2013 Jun 18;18(6):7093-102. doi: 10.3390/molecules18067093.

Abstract

Two new resveratrol trimer derivatives, named rheumlhasol A (1) and rheumlhasol B (2) were isolated from the methanolic extract of roots of Rheum lhasaense A. J. Li et P. K. Hsiao together with four known resveratrol dimer derivatives, including maximol A (3), gnetin C (4), ε-viniferin (5), and pallidol (6). The structures were determined by combined spectroscopic methods and by comparison of their spectral data with those reported in the literature. All the compounds isolated from R. lhasaense were tested for their ability to scavenge1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.

摘要

从藏边大黄 Rheum lhasaense A. J. Li et P. K. Hsiao 的甲醇提取物中分离得到两种新的白藜芦醇三聚体衍生物,命名为 rheumlhasol A(1)和 rheumlhasol B(2)。此外,还分离得到了四种已知的白藜芦醇二聚体衍生物,包括 maximol A(3)、银杏素 C(4)、ε-viniferin(5)和 pallidol(6)。结构通过综合光谱方法和与文献报道的光谱数据进行比较来确定。从藏边大黄中分离得到的所有化合物都测试了其清除 1,1-二苯基-2-苦基肼(DPPH)自由基的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5de2/6270142/59176b33830a/molecules-18-07093-g001.jpg

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