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[大黄治疗慢性肾功能衰竭的临床与实验室研究综述]

[Summarization of the clinical and laboratory study on the rhubarb in treating chronic renal failure].

作者信息

Xiao Wei, Deng Hong-zhu, Ma Yun

机构信息

Department of Chinese Traditional Medicine, First Military Medicine University, Guangzhou 510515, Guangdong, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2002 Apr;27(4):241-4, 262.

Abstract

OBJECTIVE

To review the clinical and laboratory study on the rhubarb in the treatment of Chronic Renal Failure (CRF).

METHOD

Documents of clinical and mechanism study on chinese medicine rhubarb including the simple rhubarb and the rhubarb complex prescription in which rhubarb is the main effective ingredient in recent 10 years were searched and summarized.

RESULT

Clinical application involving dosage forms, prescriptions, usage and effect of the rhubarb and its prescriptions in the treatment of the CRF and their laboratory study progress wre summarized.

CONCLUSION

Rhubarb and all kinds of its complex prescriptions have an assured effect on CRF and their mechanism includes many ways such as ameliorating azotemia, preventing nephritic compensatory hypertrophy and high metabolism situation, and so on. So the rhubarb can be used as an ideal medicine in treating CRF in a long period of time and will have a very brilliant prospect.

摘要

目的

回顾大黄治疗慢性肾衰竭(CRF)的临床及实验室研究。

方法

检索并总结近10年关于中药大黄(包括单纯大黄及以大黄为主要有效成分的复方)的临床及作用机制研究文献。

结果

总结了大黄及其方剂在治疗CRF中的临床应用,包括剂型、方剂、用法及疗效,以及其实验室研究进展。

结论

大黄及其各类复方对CRF有确切疗效,其作用机制包括改善氮质血症、防止肾代偿性肥大及高代谢状态等多种途径。因此,大黄可长期作为治疗CRF的理想药物,具有非常广阔的前景。

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