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[老年人慢性克氏锥虫(查加斯,1909年)感染相关的营养因素:班布伊项目]

[Nutritional aspects associated with chronic Trypanosoma cruzi (Chagas 1909) infection among older adults: Bambuí Project].

作者信息

Santos João Paulo dos, Lima-Costa Maria Fernanda, Peixoto Sérgio Viana

机构信息

Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brasil.

出版信息

Cad Saude Publica. 2013 Jun;29(6):1141-8.

Abstract

The aim of the study was to verify nutritional aspects associated with chronic Trypanosoma cruzi infection among baseline participants from the Bambuí cohort study on aging. The analysis included 84.9% (1,479) of residents of Bambuí, Minas Gerais State, Brazil, who were 60 years or older in 1997. T. cruzi infection was investigated by three serological tests, and nutritional status was assessed by anthropometric and biochemical variables. Associations were evaluated by prevalence ratios and confidence intervals (95%CI) using Poisson regression. T. cruzi infection was present in 38.1% of patients. All anthropometric variables were significantly associated with infection, showing lower values among patients with positive serology. No biochemical variables were associated with infection. The results showed the coexistence of chronic Chagas disease and poor nutritional status in the study population, reinforcing the importance of nutritional evaluation among elderly people presenting chronic T. cruzi infection.

摘要

该研究的目的是验证来自班布伊衰老队列研究的基线参与者中与慢性克氏锥虫感染相关的营养方面。分析纳入了巴西米纳斯吉拉斯州班布伊市84.9%(1479人)于1997年年龄在60岁及以上的居民。通过三种血清学检测调查克氏锥虫感染情况,并通过人体测量和生化变量评估营养状况。使用泊松回归通过患病率比和置信区间(95%CI)评估相关性。38.1%的患者存在克氏锥虫感染。所有人体测量变量均与感染显著相关,血清学阳性患者的值较低。没有生化变量与感染相关。结果显示研究人群中慢性恰加斯病与营养不良状况并存,这强化了对患有慢性克氏锥虫感染的老年人进行营养评估的重要性。

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