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[自体血血管内紫外线照射治疗中心性非渗出性脉络膜视网膜营养不良]

[The intravasal ultraviolet irradiation of autologous blood in the treatment of central nonexudative chorioretinal dystrophy].

作者信息

Dzhaliashvili O A, Kliavina A E, Sukhotu N Kh

出版信息

Vestn Oftalmol. 1990 Jan-Feb;106(1):41-3.

PMID:2378036
Abstract

A course of ultraviolet irradiation (UVI) of the blood, followed by reinfusion, was carried out with the use of the Izol'da MD-73 apparatus in 156 patients (300 eyes) aged 35 to 82, suffering from nonexudative chorioretinal dystrophy. The course consisted of 5 sessions with intervals of 2 days, 12-16 min each. No drugs were used during or after the treatment, except heparin (10,000 U in 50 ml of physiologic saline), that was used to wash the system of reducing pipes to prevent the formation of thrombi during blood collection and reinfusion. Vision acuity improvement, achieved in 161 cases (53.7%), has been rather stable, persisting in remote periods of the follow-up (up to 12 mos). In the rest 139 cases either improvement, that was considered unreliable, or no changes were observed immediately after UVI course. The method is simple and does not involve the use of expensive and hard-to-get imported drugs, its functional effect is sufficiently good and stable; all these factors recommend UVI for wide clinical application to the treatment of central chorioretinal dystrophy.

摘要

对156例年龄在35至82岁、患有非渗出性脉络膜视网膜营养不良的患者(300只眼),使用伊佐尔达MD - 73仪器进行了血液紫外线照射(UVI)并随后回输的疗程。该疗程包括5次治疗,间隔2天,每次12 - 16分钟。治疗期间及之后未使用任何药物,仅使用肝素(50毫升生理盐水中含10,000单位)冲洗还原管系统,以防止采血和回输过程中形成血栓。161例(53.7%)患者视力得到改善,且相当稳定,在随访的远期(长达12个月)仍持续存在。其余139例在UVI疗程后,要么改善效果不可靠,要么未观察到变化。该方法简单,不涉及使用昂贵且难以获取的进口药物,其功能效果足够良好且稳定;所有这些因素都表明UVI在临床上可广泛应用于治疗中心性脉络膜视网膜营养不良。

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