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转移性绒毛膜癌:一种罕见的以颈部肿块为表现的疾病。

Metastatic choriocarcinoma: a rare presentation as a neck mass.

作者信息

Senkal Hilmi Alper, Yılmaz Taner, Sözeri Ahmet Bülent

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Hacettepe University Hospital, Gevher Nesibe St., 06230, Sıhhiye, Ankara, Turkey.

出版信息

Ear Nose Throat J. 2013 Jun;92(6):E42. doi: 10.1177/014556131309200622.

Abstract

Testicular carcinoma metastatic to the neck is rare. Even more rare is a finding of choriocarcinoma as a neck mass without any sign of a primary testicular tumor, as only a few cases have been reported in the literature. We describe a new case that occurred in a 29-year-old man who presented with a neck mass. Fine-needle aspiration biopsy identified the tumor as a malignant epithelial neoplasm. Radiologic findings indicated the presence of a systemic metastasis of a tumor to the chest and abdomen, as well as the neck. Findings on an incisional biopsy of the neck mass were consistent with a choriocarcinoma. The testicles were normal on palpation and ultrasonography. The patient was diagnosed with metastatic choriocarcinoma with an unknown primary, and he was started on chemotherapy. On the second day of treatment, which was 25 days after his referral to our clinic, he died of respiratory insufficiency.

摘要

睾丸癌转移至颈部较为罕见。更为罕见的是,在颈部发现绒毛膜癌肿块,却无原发性睾丸肿瘤的任何迹象,因为文献中仅报道了少数病例。我们描述了一例发生在一名29岁男性身上的新病例,该患者出现颈部肿块。细针穿刺活检确定肿瘤为恶性上皮性肿瘤。影像学检查结果表明,肿瘤发生了全身转移,累及胸部、腹部以及颈部。颈部肿块的切开活检结果与绒毛膜癌相符。触诊和超声检查显示双侧睾丸正常。该患者被诊断为原发性不明的转移性绒毛膜癌,并开始接受化疗。在转诊至我们诊所25天后的治疗第二天,他因呼吸功能不全死亡。

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