Stroke and Dementia Research Centre, St George's, University of London, Cranmer Terrace, Tooting, London, SW17 0RE, UK.
Curr Atheroscler Rep. 2013 Aug;15(8):342. doi: 10.1007/s11883-013-0342-8.
Stroke represents a clinical syndrome rather than a single disease. A number of stroke subtypes can be distinguished based on careful phenotyping, with each of these having distinct and overlapping risk factor profiles. Recent evidence has suggested that genetics plays an important part in stroke risk, with at least 2 genes specific to stroke risk directly now having been identified. This review will explore our current understanding of the genetics underlying stroke risk and whether this information is currently useful in a clinical setting for patient benefit.
中风是一种临床综合征，而不是一种单一的疾病。可以根据仔细的表型分析来区分许多中风亚型，其中每一种都有不同但又有重叠的危险因素特征。最近的证据表明，遗传在中风风险中起着重要作用，至少有 2 个专门针对中风风险的基因已经被直接确定。这篇综述将探讨我们对中风风险遗传基础的现有认识，以及这些信息在临床环境中是否对患者有益。
