Ernst E, Lohmaier E F, Meurer M, Gerstmeier J
Abt. Physikalische Medizin und Rehabilitation, Medizinische Hochschule Hannover.
Z Rheumatol. 1990 May-Jun;49(3):155-9.
The aim was to define blood rheology in progressive systemic scleroderma (PSS). 55 patients were compared to controls. Blood and plasma viscosity, hematocrit, red cell aggregation, and deformability were measured. Except for hematocrit, all these variables are significantly altered, indicating a loss of blood fluidity in PSS. Drugs had no obvious effect on blood rheology, but the clinical picture did. The loss of blood fluidity in PSS is suggested to play a pathophysiological role in the initiation of Raynaud phenomena, from which all patients suffered.
目的是确定进行性系统性硬化症（PSS）患者的血液流变学特征。将55例患者与对照组进行比较。测量了血液和血浆粘度、血细胞比容、红细胞聚集性和变形性。除血细胞比容外，所有这些变量均有显著改变，表明PSS患者血液流动性降低。药物对血液流变学无明显影响，但对临床表现有影响。PSS患者血液流动性降低被认为在所有患者均出现的雷诺现象的发病机制中起病理生理作用。
