Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh-160012, India.
J Trop Pediatr. 2013 Dec;59(6):434-40. doi: 10.1093/tropej/fmt035. Epub 2013 Jun 19.
Clinical spectrum of cerebral palsy (CP) is different in developing and developed countries. We evaluated the clinical profile, etiological factors and co-morbidities of children with CP in North India, and compared with our previous study.
1212 children with CP registered in last 10 years in our rehabilitation center were compared with our previous study of 1000 children from same center.
Spastic quadriplegia is the commonest type of CP (51.5%) although lesser than previous decade (61%). Birth asphyxia remains the main (51.98%) etiological factor as earlier (45.3%). CP due to CNS infections decreased from 63.5% to 57.4%, due to bilirubin-encephalopathy remained same (∼30%). Speech problems (83.7%), microcephaly (64.27%), seizures (44.5%) and intellectual disability (38.61%) are common co-morbidities. Common neuroimaging findings include hypoxic-ischemic changes and periventricular leucomalacia.
The spectrum of CP is evolving in the developing countries with an increase in diplegic and a decrease in quadriplegic CP.
脑性瘫痪（CP）的临床谱在发展中国家和发达国家有所不同。我们评估了印度北部儿童 CP 的临床特征、病因因素和共病情况，并与我们之前的研究进行了比较。
将我们康复中心过去 10 年登记的 1212 名 CP 患儿与来自同一中心的 1000 名患儿的先前研究进行比较。
痉挛性四肢瘫是最常见的 CP 类型（51.5%），尽管低于前十年（61%）。出生窒息仍然是主要的（51.98%）病因，与之前相同（45.3%）。由于中枢神经系统感染导致的 CP 从 63.5%下降到 57.4%，由于胆红素脑病导致的 CP 保持不变（约 30%）。言语问题（83.7%）、小头畸形（64.27%）、癫痫发作（44.5%）和智力残疾（38.61%）是常见的共病。常见的神经影像学发现包括缺氧缺血性改变和脑室周围白质软化。
发展中国家 CP 的谱在不断变化，四肢瘫 CP 减少，双瘫 CP 增加。
