*College of LSA, University of Michigan, Ann-Arbor, MI †Eye Physicians & Surgeons, Milford, CT ‡Ophthalmic Consultants of the Capital Region, Albany, NY.
J Glaucoma. 2013 Oct-Nov;22(8):667-71. doi: 10.1097/IJG.0b013e31829c024c.
To describe our clinical experience with ciliary sulcus-implanted Baerveldt glaucoma tube shunts entirely concealed behind the iris in undilated pseudophakic eyes (concealed tubes, CT group), compared with similarly implanted tubes whose openings remain fully exposed in the undilated pupillary area (nonconcealed tubes, NCT group).
A retrospective interventional nonrandomized comparative chart review. The main outcome measures were postoperative tube incarceration by the iris, and postoperative intraocular pressure (IOP) and the number of IOP-lowering medications.
Fifteen eyes of 15 patients were identified in the CT group and 41 eyes of 41 patients in the NCT group. In the CT and NCT groups, the postoperative follow-up period was 14.4±10.2 months (mean±SD; range, 3 to 42 mo) and 22.9±18.1 months (mean±SD; range, 3 to 72 mo; P=0.08), respectively. Only 1 case of tube incarceration by the iris has occurred in the CT group (6.7%) and none in the NCT group. This eye was treated with laser iridotomy with no recurrence. Preoperative IOPs in the CT and the NCT groups were 27.2±9.6 mm Hg (mean±SD; range, 16 to 46 mm Hg) and 25.5±10.6 mm Hg (mean±SD; range, 12 to 59 mm Hg; P=0.6), respectively. The IOPs were significantly reduced to 13.3±4.1 mm Hg (mean±SD; range, 6 to 22 mm Hg; P=0.0001) and 10.8±4.4 mm Hg (mean±SD; range, 4 to 25 mm Hg; P=0.0001), respectively, at the final visit. The difference in the final visit IOP between the groups approached significance (P=0.056). The number of preoperative IOP-lowering medications was 3.9±0.7 (mean±SD; range, 2 to 5) and 4.0±1.0 (mean±SD; range, 1 to 6), respectively. It was significantly reduced to 1.9±1.2 (mean±SD; range, 0 to 4; P=0.0001) and 1.8±1.4 (mean±SD; range, 0 to 5; P=0.0001), respectively. There was no significant difference between the groups before (P=0.6) or after surgery (P=0.8).
Although NCTs tend to have a lower final IOP compared with CTs, the latter are safe and effective and do not require surgical repositioning. Should a CT become occluded by the iris, an uncommon event in our study, it could be treated by laser iridotomy alone.
描述我们在未散瞳的人工晶状体眼(隐蔽管组,CT 组)中将睫状沟植入的 Baerveldt 青光眼引流管完全隐藏在虹膜后面的临床经验,与管开口完全暴露在未散瞳瞳孔区域的类似植入管(非隐蔽管,NCT 组)进行比较。
回顾性干预性非随机比较图表审查。主要观察指标为术后管被虹膜嵌顿和术后眼内压(IOP)以及降低 IOP 药物的数量。
CT 组 15 例患者的 15 只眼和 NCT 组 41 例患者的 41 只眼被确定。在 CT 组和 NCT 组中,术后随访时间分别为 14.4±10.2 个月(平均值±标准差;范围,3 至 42 个月)和 22.9±18.1 个月(平均值±标准差;范围,3 至 72 个月;P=0.08)。CT 组仅发生 1 例管被虹膜嵌顿(6.7%),NCT 组未发生管被虹膜嵌顿。该眼通过激光虹膜切开术治疗,无复发。CT 组和 NCT 组术前 IOP 分别为 27.2±9.6mmHg(平均值±标准差;范围,16 至 46mmHg)和 25.5±10.6mmHg(平均值±标准差;范围,12 至 59mmHg;P=0.6)。IOP 分别显著降低至 13.3±4.1mmHg(平均值±标准差;范围,6 至 22mmHg;P=0.0001)和 10.8±4.4mmHg(平均值±标准差;范围,4 至 25mmHg;P=0.0001),在最后一次就诊时。两组间最终就诊时 IOP 的差异接近显著(P=0.056)。术前 IOP 降低药物的数量分别为 3.9±0.7(平均值±标准差;范围,2 至 5)和 4.0±1.0(平均值±标准差;范围,1 至 6)。分别显著减少至 1.9±1.2(平均值±标准差;范围,0 至 4;P=0.0001)和 1.8±1.4(平均值±标准差;范围,0 至 5;P=0.0001)。两组术前(P=0.6)或术后(P=0.8)均无显著差异。
尽管 NCT 的最终 IOP 往往低于 CT,但 CT 是安全有效的,不需要手术重新定位。如果 CT 被虹膜阻塞(在我们的研究中是一种罕见事件),可以单独通过激光虹膜切开术进行治疗。