Beaumont Eye Institute.
J Glaucoma. 2010 Aug;19(6):405-11. doi: 10.1097/IJG.0b013e3181bdb52d.
To summarize our clinical experience with implanting Baerveldt glaucoma tube shunts through the ciliary sulcus in eyes with a posterior chamber intraocular lens and shallow anterior chambers, corneal transplants, guttata or edema.
A retrospective interventional nonrandomized noncomparative case series. Main outcome measure was postoperative corneal status. Secondary outcome measures included postoperative intraocular pressure (IOP), visual acuity and complications.
Thirty-six eyes of 32 patients were identified through chart review. Follow-up period was 21.8+/-16.6 months (mean+/-standard deviation, range: 4.0 to 58.5 mo). At final visit, all 23 preoperative clear native corneas and 6 of 7 corneal transplants remained clear. Thus, of the 30 preoperative clear corneas, only 1 decompensated. Preoperative IOP was 27.9+/-11.8 mm Hg (range: 12 to 59 mm Hg), reduced postoperatively to 10.1+/-3.9 mm Hg (range: 2 to 21 mm Hg, P=0.0001), a reduction of 58.2%+/-19.3% (range: 5.0% to 95.4%). Final IOP was >or=5 and <or=21 mm Hg in 33 of 36 eyes (91.7%). It was lowered by 30% or more in 34 of 36 eyes (94.4%).
Although previously published studies demonstrated a significant risk of corneal decompensation after angle or pars plana tube implantation, our clinical experience suggests that ciliary sulcus tube implantation in eyes with a posterior chamber intraocular lens is a safe and effective procedure even in eyes with high risk of corneal decompensation.
总结我们在伴有后房型人工晶状体和浅前房、角膜移植、葡萄膜渗出或水肿的情况下,通过睫状沟植入 Baerveldt 青光眼引流管的临床经验。
回顾性介入非随机非对照病例系列研究。主要观察指标为术后角膜状况。次要观察指标包括术后眼压(IOP)、视力和并发症。
通过图表回顾共确定 32 例 36 只眼。随访时间为 21.8+/-16.6 个月(均值+/-标准差,范围:4.0 至 58.5 月)。末次随访时,23 只术前透明的天然角膜和 7 只角膜移植中的 6 只仍保持透明。因此,在 30 只术前透明的角膜中,只有 1 只出现失代偿。术前 IOP 为 27.9+/-11.8mmHg(范围:12 至 59mmHg),术后降低至 10.1+/-3.9mmHg(范围:2 至 21mmHg,P=0.0001),降低了 58.2%+/-19.3%(范围:5.0%至 95.4%)。36 只眼中 33 只(91.7%)最终 IOP≥5mmHg 且<21mmHg。36 只眼中 34 只(94.4%)眼压降低了 30%或更多。
尽管之前的研究表明,在角巩膜或巩膜隧道植入管后,角膜失代偿的风险显著增加,但我们的临床经验表明,在后房型人工晶状体眼的睫状沟植入管是一种安全有效的手术方法,即使在角膜失代偿风险高的情况下也是如此。