Ross Richard J, Shayan Ramin, Mutimer Keith L, Ashton Mark W
From the *Taylor Laboratory, Department of Anatomy and Neurosciences, University of Melbourne; †Department of Plastic and Reconstructive Surgery, Royal Melbourne Hospital and University of Melbourne, Parkville; and ‡Australian Catholic University, Victoria Pde, Fitzroy, Victoria, Australia.
Ann Plast Surg. 2014 Sep;73(3):352-7. doi: 10.1097/SAP.0b013e31827aeb51.
Despite the widespread use of autologous fat grafting in both reconstructive and cosmetic surgery, volume retention remains a significant problem. We aimed to critically appraise the current body of literature in fat grafting to provide a framework to guide application and comparison.
Search of scientific databases and gray literature was conducted. Articles examining nonadipogenic applications of adipose tissue and those specific to breast reconstruction were excluded.
One hundred three articles were included. These fell under the headings of donor site, effect of infiltration solution, harvest method, effect of centrifugation, reinjection method, supplementation, the role of adipose-derived stem cells, and scaffolding.
Despite the significant research effort in this field, there remains no consensus as to the optimum technique. This stems from the vast array of research methods and short follow-up durations. Further, extrapolation of in vitro results to clinical settings has led to many conflicting practices.
尽管自体脂肪移植在重建手术和美容手术中都得到了广泛应用,但体积保留仍然是一个重大问题。我们旨在对目前脂肪移植方面的文献进行批判性评估,以提供一个指导应用和比较的框架。
对科学数据库和灰色文献进行了检索。排除了研究脂肪组织非脂肪生成应用的文章以及特定于乳房重建的文章。
纳入了103篇文章。这些文章分为供区、浸润液的作用、采集方法、离心的作用、再注射方法、补充、脂肪来源干细胞的作用以及支架等类别。
尽管该领域进行了大量研究,但对于最佳技术仍未达成共识。这源于大量的研究方法和较短的随访时间。此外,将体外结果外推至临床环境导致了许多相互矛盾的做法。