Department of Dermatology, Hospital of Weifang People.
Institute of Plastic Surgery, Weifang Medical University, Shandong, China.
J Craniofac Surg. 2022;33(1):108-111. doi: 10.1097/SCS.0000000000008038.
Autologous fat grafting is commonly used for soft tissue augmentation and reconstruction, this technique is limited by a high rate of graft absorption. The stromal vascular fraction gel (SVF-gel) grafting for facial volume augmentation can exert a positive effect on skin rejuvenation, but its major limitation is the low rate of conversion of Coleman fat. The purpose of our study was to investigate a novel surgery using performing high-density fat in combination with SVF-gel in the treatment of hemifacial atrophy, or Romberg diseases. From October 2017 to October 2019, 13 patients with hemifacial atrophy underwent high-density fat transfer with SVF-gel injection. The outcome was determined by the difference in presurgery and postsurgery FACE-Q modules (FACE-Q conceptual framework: 1, Satisfaction with Facial Appearance; 2, Health-Related Quality of Life; 3, Negative Sequelae; 4, Satisfaction with Process of Care), which were designed as patient-reported outcome instrument to evaluate the unique outcomes of patients undergoing facial cosmetic procedures.The excellent cosmetic results were observed during follow-up periods, with no adverse events was seen in the treatment group. All patients showed improvements in facial augmentation and contour. In patients with facial volume loss, high-density fat transfer with SVF-gel facial injection resulted in significantly higher improvement scores and better patient satisfaction. The patient-reported FACE-Q modules presurgery and postsurgery results showed statistically significant improvement (P < 0.05). This high-density fat in combination with SVF-gel is an effective method of correcting the facial volume loss that leave no complications during follow-up, having a satisfactory volumization effect. This could largely facilitate the clinical utilization of fat.
自体脂肪移植常用于软组织填充和重建，但其吸收率较高限制了其应用。基质血管成分凝胶（SVF-gel）用于面部容量填充可以对面部年轻化产生积极影响，但主要限制是Coleman 脂肪转化率低。本研究旨在探讨一种使用高密度脂肪结合 SVF-gel 治疗半侧颜面萎缩或 Romberg 病的新型手术。2017 年 10 月至 2019 年 10 月，13 例半侧颜面萎缩患者接受了高密度脂肪转移联合 SVF-gel 注射。通过术前和术后 FACE-Q 模块（FACE-Q 概念框架：1. 面部外观满意度；2. 健康相关生活质量；3. 负面后遗症；4. 护理过程满意度）的差异来确定结果，该模块是专门设计为患者报告的评估面部美容手术患者独特结果的工具。在随访期间观察到了良好的美容效果，治疗组无不良事件发生。所有患者的面部填充和轮廓均有改善。在面部容量丧失的患者中，高密度脂肪转移联合 SVF-gel 面部注射可显著提高改善评分和患者满意度。患者报告的 FACE-Q 模块术前和术后结果显示有统计学意义的改善（P<0.05）。这种高密度脂肪结合 SVF-gel 是一种纠正面部容量丧失的有效方法，在随访期间无并发症，具有令人满意的容量填充效果。这在很大程度上促进了脂肪的临床应用。
