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大量体重减轻后的大腿松弛:效用结果评估

Thigh laxity after massive weight loss: a utilities outcomes assessment.

作者信息

Izadpanah Ali, Sinno Hani, Vorstenbosch Joshua, Lee Bernard T, Lin Samuel J

机构信息

Division of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, Quebec, Canada.

出版信息

Ann Plast Surg. 2013 Sep;71(3):304-7. doi: 10.1097/SAP.0b013e3182834b88.

Abstract

BACKGROUND

The presence of excess skin after massive weight loss, particularly in the thighs, not only contributes to a negative body image but can also lead to functional deficits in mobility. In the present study, we quantified the health state utility of living with excess skin in the thighs in an attempt to objectively establish the burden on the quality of life in patients living with excess thigh skin laxity.

METHOD

Using visual analog scale (VAS), time trade-off (TTO), and standard gamble (SG), we compared the utility outcome scores for thigh skin excess with monocular and binocular blindness from a prospective sample of medical students and the general population. Utility scores were compared using paired t test. Linear regression was performed using age, race, and education as independent predictors of each of the utility scores.

RESULTS

One hundred thirty-four prospective participants were enrolled during a 6-month period, and 112 participants met our inclusion criteria. The utility outcome scores for thigh lift (VAS, TTO, and SG, 0.77 ± 0.15, 0.90 ± 0.11, and 0.89 ± 0.14, respectively) were statistically different from binocular blindness (VAS, TTO, and SG, 0.37 ± 0.18, 0.70 ± 0.23, and 0.70 ± 0.26; P < 0.001), but other than VAS (0.67 ± 0.15, P < 0.001), similar to monocular blindness (TTO and SG, 0.89 ± 0.13 and 0.81 ± 0.14, respectively; P > 0.05). SG (0.89 ± 0.14 vs 0.97 ± 0.02, P = 0.003) and TTO (0.89 ± 0.11 vs 0.95 ± 0.03, P = 0.038) were different between general population and medical students, respectively, corresponding to 3.96 versus 1.80 potential years willing to be traded (P < 0.05). Additionally, SG was higher in whites versus nonwhites who were willing to take a potential 8% chance of mortality compared to 15%, respectively (P = 0.001), to achieve "perfect" health.

CONCLUSIONS

We have objectified the utility of living with thigh deformity after massive weight loss. Our sample population if faced with the condition was willing to sacrifice a potential 3.6 years of life and potentially undergo a procedure with 11% chance of mortality to address excess thigh laxity.

摘要

背景

大量体重减轻后出现多余皮肤,尤其是在大腿部位,不仅会导致负面的身体形象,还可能导致行动功能障碍。在本研究中,我们对大腿部有多余皮肤的生活健康状态效用进行了量化,试图客观确定大腿皮肤过度松弛患者的生活质量负担。

方法

我们使用视觉模拟量表(VAS)、时间权衡法(TTO)和标准博弈法(SG),对来自医学生和普通人群的前瞻性样本中大腿皮肤多余情况与单眼和双眼失明的效用结果得分进行了比较。效用得分采用配对t检验进行比较。以年龄、种族和教育程度作为每个效用得分的独立预测因素进行线性回归分析。

结果

在6个月期间招募了134名前瞻性参与者,112名参与者符合我们的纳入标准。大腿提升术的效用结果得分(VAS、TTO和SG分别为0.77±0.15、0.90±0.11和0.89±0.14)与双眼失明(VAS、TTO和SG分别为0.37±0.18、0.70±0.23和0.70±0.26;P<0.001)在统计学上有差异,但除VAS外(0.67±0.15,P<0.001),与单眼失明相似(TTO和SG分别为0.89±0.13和0.81±0.14;P>0.05)。普通人群和医学生之间SG(0.89±0.14对0.97±0.02,P=0.003)和TTO(0.89±0.11对0.95±0.03,P=0.038)分别不同,相当于愿意交换的潜在年数为3.96年对1.80年(P<0.05)。此外,在愿意接受分别为8%和15%的潜在死亡风险以实现“完美”健康的情况下,白人的SG得分高于非白人(P=0.001)。

结论

我们已客观确定了大量体重减轻后大腿畸形生活的效用。我们的样本人群若面临这种情况,愿意牺牲潜在的3.6年寿命,并可能接受有11%死亡风险的手术来解决大腿过度松弛问题。

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