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整形外科学术文献中健康状态效用值的系统评价

A Systematic Review of Health State Utility Values in the Plastic Surgery Literature.

作者信息

Christopher Adrienne N, Morris Martin P, Patel Viren, Klifto Kevin, Fischer John P

机构信息

Division of Plastic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.

Department of Surgery, Thomas Jefferson University, Philadelphia, Pa.

出版信息

Plast Reconstr Surg Glob Open. 2021 Nov 29;9(11):e3944. doi: 10.1097/GOX.0000000000003944. eCollection 2021 Nov.

Abstract

UNLABELLED

Cost-utility analyses assess health gains acquired by interventions by incorporating weighted health state utility values (HSUVs). HSUVs are important in plastic and reconstructive surgery (PRS) because they include qualitative metrics when comparing operative techniques or interventions. We systematically reviewed the literature to identify the extent and quality of existing original utilities research within PRS.

METHODS

A systematic review of articles with original PRS utility data was conducted in accordance with the Preferred Reporting Items for a Systematic Review and Meta-Analysis guidelines. Subspecialty, survey sample size, and respondent characteristics were extracted. For each HSUV, the utility measure [direct (standard gamble, time trade off, visual analog scale) and/or indirect], mean utility score, and measure of variance were recorded. Similar HSUVs were pooled into weighted averages based on sample size if they were derived from the same utility measure.

RESULTS

In total, 348 HSUVs for 194 disease states were derived from 56 studies within seven PRS subspecialties. Utility studies were most common in breast (n = 17, 30.4%) and hand/upper extremity (n = 15, 26.8%), and direct measurements were most frequent [visual analog scale (55.4%), standard gamble (46.4%), time trade off (57.1%)]. Studies surveying the general public had more respondents (n = 165, IQR 103-299) than those that surveyed patients (n = 61, IQR 48-79) or healthcare professionals (n = 42, IQR 10-109). HSUVs for 18 health states were aggregated.

CONCLUSIONS

The HSUV literature within PRS is scant and heterogeneous. Researchers should become familiar with these outcomes, as integrating utility and cost data will help illustrate that the impact of certain interventions are cost-effective when we consider patient quality of life.

摘要

未标注

成本效用分析通过纳入加权健康状态效用值(HSUVs)来评估干预措施所获得的健康收益。HSUVs在整形和重建手术(PRS)中很重要,因为在比较手术技术或干预措施时,它们纳入了定性指标。我们系统地回顾了文献,以确定PRS中现有原始效用研究的范围和质量。

方法

根据系统评价和Meta分析的首选报告项目指南,对具有原始PRS效用数据的文章进行了系统评价。提取了亚专业、调查样本量和受访者特征。对于每个HSUV,记录效用测量方法[直接(标准博弈、时间权衡、视觉模拟量表)和/或间接]、平均效用得分和方差测量值。如果相似的HSUVs来自相同的效用测量方法,则根据样本量将其合并为加权平均值。

结果

总共从七个PRS亚专业的56项研究中得出了194种疾病状态的348个HSUVs。效用研究在乳房(n = 17,30.4%)和手/上肢(n = 15,26.8%)方面最为常见,直接测量最为频繁[视觉模拟量表(55.4%)、标准博弈(46.4%)、时间权衡(57.1%)]。调查普通公众的研究比调查患者(n = 61,IQR为48 - 79)或医疗保健专业人员(n = 42,IQR为10 - 109)的研究有更多的受访者(n = 165,IQR为103 - 299)。汇总了18种健康状态的HSUVs。

结论

PRS中的HSUV文献稀少且参差不齐。研究人员应熟悉这些结果,因为整合效用和成本数据将有助于说明,当我们考虑患者生活质量时,某些干预措施的影响具有成本效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/8615317/913123cb0a1a/gox-9-e3944-g001.jpg

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