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益生菌嗜酸乳杆菌La-14的全基因组序列

Complete Genome Sequence of Probiotic Strain Lactobacillus acidophilus La-14.

作者信息

Stahl Buffy, Barrangou Rodolphe

机构信息

DuPont Nutrition and Health, Madison, Wisconsin, USA.

出版信息

Genome Announc. 2013 Jun 20;1(3):e00376-13. doi: 10.1128/genomeA.00376-13.

DOI:10.1128/genomeA.00376-13
PMID:23788546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3707595/
Abstract

We present the 1,991,830-bp complete genome sequence of Lactobacillus acidophilus strain La-14 (SD-5212). Comparative genomic analysis revealed 99.98% similarity overall to the L. acidophilus NCFM genome. Globally, 111 single nucleotide polymorphisms (SNPs) (95 SNPs, 16 indels) were observed throughout the genome. Also, a 416-bp deletion in the LA14_1146 sugar ABC transporter was identified.

摘要

我们公布嗜酸乳杆菌菌株La-14（SD-5212）的1,991,830碱基对完整基因组序列。比较基因组分析显示，其与嗜酸乳杆菌NCFM基因组的总体相似度为99.98%。在全基因组范围内，共观察到111个单核苷酸多态性（SNP）（95个SNP，16个插入缺失）。此外，还在LA14_1146糖ABC转运蛋白中发现了一个416碱基对的缺失。

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本文引用的文献

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