Universidade Estadual do Ceará, Fortaleza, CE, Brazil.
J Pediatr (Rio J). 2013 Jul-Aug;89(4):400-6. doi: 10.1016/j.jped.2012.12.009. Epub 2013 Jun 20.
To analyze the profile of blood transfusion reactions in children and to identify the involved factors.
This was a cross-sectional study in a tertiary pediatric teaching hospital from the public healthcare system, involving all children admitted from January to July of 2011 (5,437), of which 1,226 received blood transfusions, constituting the sample. A documental study was performed by analyzing files from the hemovigilance service and notification forms of transfusion reactions. The variables investigated were: number and type of blood components transfused, transfusion site, reaction site, age, gender, type of blood components involved, type of incident, and previous history of multiple transfusions. A descriptive and inferential analysis was performed, using statistical tests to establish the association between the variables.
There were 57 transfusion incidents involving 47 children and 72 different blood products, thus constituting a prevalence of reactions of 3.8%. At the inferential analysis, the chi-squared test showed that the following variables were significantly associated (p<0.05) with the type of reaction: age range and type of blood component. Similarly, the patient's underlying disease was associated with previous history of transfusion incident and type of blood component.
The prevalence of transfusion reactions in children is high, and the intervening factors are: type of blood component, age, patient comorbidity, and multiple transfusions; type of blood component and age are also associated with type of reaction.
分析儿童输血反应的特征，并确定相关因素。
这是一项在公立医疗系统的三级儿科教学医院进行的横断面研究，涉及 2011 年 1 月至 7 月期间入院的所有儿童（5437 名），其中 1226 名接受了输血，构成了样本。通过分析血液监测服务和输血反应报告表中的文件，进行了一项文献研究。研究的变量包括：输注的血液成分的数量和类型、输血部位、反应部位、年龄、性别、涉及的血液成分类型、事件类型以及多次输血的既往史。采用描述性和推断性分析，使用统计检验来确定变量之间的关联。
共有 57 起涉及 47 名儿童和 72 种不同血液制品的输血事件，因此反应发生率为 3.8%。在推断性分析中，卡方检验显示以下变量与反应类型显著相关（p<0.05）：年龄范围和血液成分类型。同样，患者的基础疾病与既往输血事件和血液成分类型有关。
儿童输血反应的发生率较高，相关因素包括：血液成分类型、年龄、患者合并症和多次输血；血液成分类型和年龄也与反应类型有关。
