Fowler S A, Gaertner K L
Chicago College of Osteopathic Medicine, Department of Ophthalmology, Downers Grove, IL 60515.
CLAO J. 1990 Jul-Sep;16(3):214-8.
Deposits are a complication of contact lens wear that have been associated with ocular diseases, including keratitis and giant papillary conjunctivitis. The purpose of this morphologic study was to describe the deposits on soft contact lenses fabricated by different surface manufacturing methods and to evaluate the ease of removal of deposits by surfactant cleaning. We studied the anterior surfaces of 30 soft contact lenses (10 lathe cut [polished]; 10 spin cast [unpolished], and 10 cast molded [unpolished]) of the same polymer and water content. All lenses were worn for 8 hours by two asymptomatic persons who did not routinely wear contact lenses. Lenses from one eye were immersed in glutaraldehyde, while lenses from the other eye were cleaned before immersion in glutaraldehyde. All lenses were then dehydrated in graded alcohols, critical-point-dried, and observed by scanning electron microscopy. The amount of deposit on the lens surface was judged by an individual who did not know the identity of the lens. All lenses showed similar types of deposits. At the end of 8 hours wear, all types of lens surfaces were covered with deposits. Cleaning removed some but not all deposits. The lens surfaces manufactured in such a way as to leave polishing or lathe marks showed deposits "heaped-up" on the marks before cleaning and remaining in the mark after cleaning. Polishing marks from lens fabrication may represent an increased risk for conjunctival insult from deposits remaining in the marks after cleaning.
沉积物是隐形眼镜佩戴的一种并发症，与眼部疾病有关，包括角膜炎和巨乳头性结膜炎。本形态学研究的目的是描述通过不同表面制造方法制造的软性隐形眼镜上的沉积物，并评估表面活性剂清洁去除沉积物的难易程度。我们研究了30片相同聚合物和含水量的软性隐形眼镜的前表面（10片车床切割[抛光]；10片旋转浇铸[未抛光]，以及10片铸模成型[未抛光]）。两名无症状且非经常佩戴隐形眼镜的人佩戴所有镜片8小时。一只眼睛的镜片浸泡在戊二醛中，而另一只眼睛的镜片在浸泡在戊二醛之前进行清洁。然后所有镜片在分级酒精中脱水、临界点干燥，并通过扫描电子显微镜观察。镜片表面沉积物的量由一名不知道镜片身份的人员判断。所有镜片都显示出相似类型的沉积物。佩戴8小时结束时，所有类型镜片表面都覆盖有沉积物。清洁去除了部分但不是所有沉积物。以留下抛光或车床痕迹方式制造的镜片表面，在清洁前沉积物“堆积”在痕迹上，清洁后仍留在痕迹中。镜片制造过程中的抛光痕迹可能意味着清洁后留在痕迹中的沉积物对结膜造成损伤的风险增加。
