Centre for Health Policy and Management, Trinity College Dublin, Dublin, Republic of Ireland.
BMJ Open. 2013 Jun 21;3(6):e002571. doi: 10.1136/bmjopen-2013-002571.
Multimorbidity is common in the older population, but the impact of combinations of chronic conditions on disability and quality of life (QoL) is not well known. This analysis explores the effect of specific combinations of chronic diseases on disability, QoL and self-rated health (SRH).
We used data from two population representative cross-sectional studies, the Northern Ireland Health and Social Wellbeing Survey (NIHSWS) 2005 and the Survey of Lifestyle, Attitudes and Nutrition (SLAN) 2007 (conducted in the Republic of Ireland).
Randomly selected community-living participants were interviewed at home.
A total of 6159 participants aged 50 years and older were included in the analysis.
Chronic conditions were classified as cardiovascular disease, chronic pain, diabetes or respiratory disease. Interaction terms estimated by logistic regression were used to examine the effects of multiple chronic conditions on disability, SRH and QoL.
Each chronic condition group was correlated with each of the others after adjusting for sociodemographic factors. Those from Northern Ireland were more likely to report a limitation in daily activities (45%) compared to those from the Republic of Ireland (21%). Each condition had an independent effect on disability, SRH and QoL, and those with multiple chronic conditions reported the worst outcomes. However, there were no statistically significant positive interactions between chronic condition groups with respect to any outcome.
Chronic conditions affect individuals largely independent of each other with respect to their effect on disability, SRH and QoL. However, a significant proportion of the population aged 50 years and over across the island of Ireland lives with multimorbidity, and this group is at the highest risk of disability, poor SRH and poor QoL.
多病共存在老年人群中很常见,但慢性疾病组合对残疾、生活质量(QoL)的影响尚不清楚。本分析探讨了特定慢性疾病组合对残疾、QoL 和自我评估健康(SRH)的影响。
我们使用了两项具有代表性的人群横断面研究的数据,即北爱尔兰健康和社会福利调查(NIHSWS)2005 年和生活方式、态度和营养调查(SLAN)2007 年(在爱尔兰共和国进行)。
在家中对随机选择的社区居住参与者进行访谈。
共有 6159 名年龄在 50 岁及以上的参与者纳入分析。
慢性疾病分为心血管疾病、慢性疼痛、糖尿病或呼吸系统疾病。通过逻辑回归估计的交互项用于检查多种慢性疾病对残疾、SRH 和 QoL 的影响。
在调整了社会人口因素后,每个慢性疾病组都与其他组相关。与爱尔兰共和国的参与者(21%)相比,来自北爱尔兰的参与者更有可能报告日常活动受限(45%)。每种疾病对残疾、SRH 和 QoL 都有独立的影响,且患有多种慢性疾病的患者报告的结果最差。然而,在任何结局方面,慢性疾病组之间没有统计学上显著的正交互作用。
慢性疾病对个体的影响在很大程度上是相互独立的,就其对残疾、SRH 和 QoL 的影响而言。然而,爱尔兰岛 50 岁及以上的人群中有相当大的比例患有多种慢性疾病,这群人面临着最高的残疾、较差的 SRH 和较差的 QoL 风险。