具有胰脂肪酶抑制活性的西托海绵酸甲酯的简洁合成。
A concise synthesis of xestospongic acid methyl ester with pancreatic lipase inhibitory activity.
作者信息
Gong Jing-Xu, Wang He-Yao, He Wen-Fei, Wang Zhen-Zhong, Xiao Wei, Guo Yue-Wei
机构信息
a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai , 201203 , China.
出版信息
J Asian Nat Prod Res. 2013;15(8):916-9. doi: 10.1080/10286020.2013.804815. Epub 2013 Jun 25.
PMID:23796323
Abstract
Xestospongic acid methyl ester, a naturally brominated fatty acid with potent pancreatic lipase inhibitory activity in vitro, was synthesized from 5-hexynol in 30% total yield.
摘要
西托海绵酸甲酯是一种天然溴化脂肪酸，在体外具有强大的胰脂肪酶抑制活性，它由5-己炔醇合成，总产率为30%。
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