Vandenbos F, Figueredo M, Dumon-Gubeno M-C, Nicolle I, Tarhini A, Butori C, Mouroux J
Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France; Centre de soins de suite et de rééducation « La Maison du Mineur », 577, avenue Henri-Giraud, 06141 Vence cedex, France.
Rev Pneumol Clin. 2013 Oct;69(5):291-3. doi: 10.1016/j.pneumo.2013.04.004. Epub 2013 Jun 21.
Malignant mesothelioma is a relatively uncommon malignancy. Although the pathogenesis is primarily related to asbestos, the role of ionizing radiation is more controversial. We report the case of a 41-year-old male who developed pleural mesothelioma. He had both, a prior short asbestos exposure and a thoracic radiotherapy for Hodgkin's disease 26years before. The evidence for radiotherapy as cause for mesothelioma is expanding and the diagnosis of mesothelioma in patients who had previous irradiation should be kept in mind.
恶性间皮瘤是一种相对罕见的恶性肿瘤。虽然其发病机制主要与石棉有关，但电离辐射的作用更具争议性。我们报告一例41岁男性发生胸膜间皮瘤的病例。他既往有短期石棉接触史，并且在26年前因霍奇金病接受过胸部放疗。放疗作为间皮瘤病因的证据正在增多，对于曾接受过放疗的患者，应考虑间皮瘤的诊断。
