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“乳头状主胰管内陷”胰肠吻合术在正常软胰腺病例中的应用。

Application of "papillary-like main pancreatic duct invaginated" pancreaticojejunostomy for normal soft pancreas cases.

机构信息

Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, P.R. China.

出版信息

Sci Rep. 2013;3:2068. doi: 10.1038/srep02068.

Abstract

Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. Our study introduced a new pancreaticojejunal (PJ) anastomosis named "papillary-like main pancreatic duct invaginated" pancreaticojejunostomy. Nighty-two patients underwent pancreaticojejunostomy with either conventional duct-to-mucosa pancreaticojejunostomy or the new "papillary-like main pancreatic duct invaginated" techniques were analyzed retrospectively from January 2010 to September 2012. The incidence of pancreatic fistula was 15.7% (8/51) for the "papillary-like main pancreatic duct invaginated" group and 19.5% (8/41) for the duct-to-mucosa fashion respectively. It is noteworthy that the rate of grade B/C postoperative pancreatic fistula (POPF) in the "papillary-like main pancreatic duct invaginated" group was significantly lower than that of the duct-to-mucosa group (P = 0.039). There were no differences in the incidence of postoperative morbidity and mortality such as postoperative hemorrhage, delayed gastric emptying or remnant pancreatitis. The "papillary-like main pancreatic duct invaginated" pancreaticojejunostomy could provide a feasible option to pancreatic surgeons for patients with normal soft pancreas.

摘要

胰肠吻合术是胰十二指肠切除术的关键步骤。我们介绍了一种新的胰肠吻合术,命名为“乳头样主胰管内陷”胰肠吻合术。回顾性分析了 2010 年 1 月至 2012 年 9 月期间 92 例行胰肠吻合术的患者,其中 51 例行传统的胰管黏膜吻合术,41 例行新的“乳头样主胰管内陷”技术。胰瘘的发生率分别为“乳头样主胰管内陷”组 15.7%(8/51)和胰管黏膜吻合组 19.5%(8/41)。值得注意的是,“乳头样主胰管内陷”组术后 B/C 级胰瘘(POPF)的发生率明显低于胰管黏膜吻合组(P=0.039)。术后出血、胃排空延迟或残胰腺炎等术后并发症和死亡率无差异。对于胰腺质地正常的患者,“乳头样主胰管内陷”胰肠吻合术可为胰腺外科医生提供一种可行的选择。

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