Department of Pediatrics, Jaslok Hospital and Research Centre, Dr G Deshmukh Marg, Mumbai, India. Correspondence to: Dr Raju P Khubchandani, 31, Kailas Darshan, Near Kennedy Bridge, Nana Chowk, Mumbai 400 007, India.
Indian Pediatr. 2013 Oct;50(10):961-3. doi: 10.1007/s13312-013-0260-4. Epub 2013 Apr 5.
A retrospective assessment of clinical characteristics, complications/ associations, laboratory investigations, treatment modalities and outcome in an inceptional cohort of 22 (male-13) children with juvenile dermatomyositis (JDM) receiving treatment at Jaslok Hospital, Mumbai during 1997- 2012 was performed . Mean age at diagnosis was 7.52 ± 3.99 years. Typical skin rash and muscle weakness were present in all children. Common complications included cutaneous ulcers (27.27%), dysphagia (22.72%) and calcinosis (18.18%).All patients presented with at least one of the serum muscle enzymes elevated. Absence of mortality and cardio-pulmonary complications and a monocyclic course in 72.7% of our patients are at variance from Western series.
回顾性评估了 1997 年至 2012 年在孟买 Jaslok 医院接受治疗的 22 例（男性 13 例）幼年特发性皮肌炎（JDM）患儿的临床特征、并发症/关联、实验室检查、治疗方式和结局。诊断时的平均年龄为 7.52±3.99 岁。所有患儿均存在典型皮疹和肌无力。常见并发症包括皮肤溃疡（27.27%）、吞咽困难（22.72%）和钙沉积（18.18%）。所有患者均至少有一种血清肌肉酶升高。与西方系列相比，我们的患者死亡率和心肺并发症为零，且 72.7%的患者为单环病程。
