All India Institute of Medical Sciences, Delhi,*Swami Dayanand Hospital, #Kasturba Hospital and $Indian Council of Medical Research, New Delhi, India. Correspondence to: Dr Ramesh Agarwal, Associate Professor, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India.
Indian Pediatr. 2013 Oct;50(10):951-3. doi: 10.1007/s13312-013-0257-z. Epub 2013 Apr 5.
Serum retinol levels of low birth weight (LBW; birth weight < 2500 g) and normal birth weight (NBW; birth weight ≥ 2500 g) infants were evaluated at birth and 3 months using high performance liquid chromatography. At birth, levels were 13.3 ± 8.2 ug/dL in LBW (n=146) and 14.0 ± 6.2 ug/dL in NBW infants (n = 79; p = 0.51), with 41.1% of LBW and 24.1% of NBW infants having vitamin A deficiency (VAD, < 10 ug/dL; P = 0.01). At follow up, levels were 18.0 ± 9.4 ug/dL in LBW (n = 83) and 20.0 ± 7.3 ug/dL in NBW infants (n = 51; P = 0.19), with 18.1% of LBW and 3.9% of NBW infants having VAD (P = 0.02).
采用高效液相色谱法检测了低出生体重儿（出生体重<2500g）和正常出生体重儿（出生体重≥2500g）出生时和 3 个月时的血清视黄醇水平。出生时，低出生体重儿为 13.3±8.2μg/dL（n=146），正常出生体重儿为 14.0±6.2μg/dL（n=79；p=0.51），41.1%的低出生体重儿和 24.1%的正常出生体重儿存在维生素 A 缺乏症（VAD，<10μg/dL；P=0.01）。随访时，低出生体重儿为 18.0±9.4μg/dL（n=83），正常出生体重儿为 20.0±7.3μg/dL（n=51；P=0.19），18.1%的低出生体重儿和 3.9%的正常出生体重儿存在 VAD（P=0.02）。
