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低出生体重和正常出生体重婴儿出生时及婴儿早期的铁储备情况。

Iron stores in low and normal birth weight infants at birth and in early infancy.

作者信息

Agarwal Ramesh, Virmani Deenanath, Jaipal Munnalal, Gupta Shuchita, Sankar Mari Jeeva, Bhatia Sunita, Agarwal Anand, Devgan Veena, Gupta Nandita, Deorari Ashok K, Paul Vinod K

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India,

出版信息

Indian J Pediatr. 2014 Mar;81(3):279-82. doi: 10.1007/s12098-013-1176-7. Epub 2013 Aug 27.

DOI:10.1007/s12098-013-1176-7
PMID:23979924
Abstract

Serum ferritin levels of low birth weight (LBW; BW < 2,500 g) and normal birth weight (NBW; BW ≥ 2,500 g) infants were evaluated at birth and at 3 mo using electrochemiluminescence immunoassay. At birth, levels were 318.6 (31.0-829.5) ng/mL in LBW (n = 217) and 366.2 (122.4-858.5) ng/mL in NBW infants (n = 116; p < 0.01), with 1.4 % of LBW and none of the NBW infants having levels <12 ng/mL (p = 0.20). At follow up, levels were 66.9 (4.5-567.7) ng/mL in LBW (n = 126) and 126.2 (6.8-553.7) ng/mL in NBW infants (n = 76; p = 0.27), with 11.9 % of LBW and 11.8 % of NBW infants having levels <12 ng/mL (p = 0.80).

摘要

采用电化学发光免疫分析法对低出生体重(LBW;体重<2500克)和正常出生体重(NBW;体重≥2500克)婴儿出生时及3个月时的血清铁蛋白水平进行评估。出生时,LBW婴儿(n = 217)的血清铁蛋白水平为318.6(31.0 - 829.5)ng/mL,NBW婴儿(n = 116)为366.2(122.4 - 858.5)ng/mL(p < 0.01),LBW婴儿中有1.4%血清铁蛋白水平<12 ng/mL,NBW婴儿中无此情况(p = 0.20)。随访时,LBW婴儿(n = 126)的血清铁蛋白水平为66.9(4.5 - 567.7)ng/mL,NBW婴儿(n = 76)为126.2(6.8 - 553.7)ng/mL(p = 0.27),LBW婴儿中有11.9%、NBW婴儿中有11.8%血清铁蛋白水平<12 ng/mL(p = 0.80)。

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2
Iron supplements reduce the risk of iron deficiency anemia in marginally low birth weight infants.铁补充剂可降低低出生体重边缘儿铁缺乏性贫血的风险。
Pediatrics. 2010 Oct;126(4):e874-83. doi: 10.1542/peds.2009-3624. Epub 2010 Sep 6.
3
Research needed to strengthen science and programs for the control of iron deficiency and its consequences in young children.
需要开展研究以加强科学和项目,用于控制幼儿缺铁及其后果。
J Nutr. 2008 Dec;138(12):2542-6. doi: 10.3945/jn.108.094888.
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Conclusions and recommendations of the WHO Consultation on prevention and control of iron deficiency in infants and young children in malaria-endemic areas.世界卫生组织关于疟疾流行地区婴幼儿缺铁预防与控制磋商会的结论与建议
Food Nutr Bull. 2007 Dec;28(4 Suppl):S621-7. doi: 10.1177/15648265070284s414.
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The assessment of newborn iron stores at birth: a review of the literature and standards for ferritin concentrations.出生时新生儿铁储备的评估:文献综述及铁蛋白浓度标准
Neonatology. 2007;92(2):73-82. doi: 10.1159/000100805. Epub 2007 Mar 14.
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