一名葡萄糖-6-磷酸脱氢酶缺乏患者发生嗜麦芽窄食单胞菌感染。
Stenotrophomonas infection in a patient with glucose-6-phosphate dehydrogenase deficiency.
作者信息
Harthan Aaron A, Heger Margaret L
机构信息
Department of Pharmacy, Children's Hospital of Illinois, Peoria, Illinois.
出版信息
J Pediatr Pharmacol Ther. 2013 Apr;18(2):137-41. doi: 10.5863/1551-6776-18.2.137.
Abstract
The drug of choice for treatment of Stenotrophomonas maltophilia is sulfamethoxazole/trimethoprim, and second-line therapy usually consists of a fluoroquinolone. However, in patients with glucose-6-phosphate dehydrogenase deficiency, neither sulfamethoxazole/trimethoprim nor a fluoroquinolone is a preferred option as it may result in hemolysis. Currently, there is a paucity of data regarding treatment of S maltophilia infection in these patients. This case report presents a patient who was successfully treated with doxycycline and inhaled colistimethate.
摘要
嗜麦芽窄食单胞菌感染的治疗首选药物是磺胺甲恶唑/甲氧苄啶，二线治疗通常包括氟喹诺酮类药物。然而，对于葡萄糖-6-磷酸脱氢酶缺乏的患者，磺胺甲恶唑/甲氧苄啶和氟喹诺酮类药物都不是首选，因为这可能会导致溶血。目前，关于这些患者嗜麦芽窄食单胞菌感染治疗的数据很少。本病例报告介绍了一名成功接受强力霉素和吸入性多粘菌素甲磺酸钠治疗的患者。
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