Kohri K, Umekawa T, Ishikawa Y, Katayama Y, Kodama M, Takada M, Katoh Y, Kataoka K, Iguchi M, Kurita T
Department of Urology, Kiniki Unversity School of Medicine, Osaka, Japan.
Int Urol Nephrol. 1990;22(1):13-23. doi: 10.1007/BF02550431.
Factors relating alterations in plasma and urine composition to recurrence of urinary stones during drug therapy were investigated by using a multiple regression analysis technique. These factors were influenced not only by the efficacy of the drugs but also by other factors (plasma or urinary constituents and overall health of the patients, etc.). In order to study the effect of drug therapy or other treatment on the alteration of plasma and urine constituents, multiple regression analysis is more appropriate than Student's paired t-test which has been used by some workers. These two analytical methods yield different results even if used on the same data.
采用多元回归分析技术，对药物治疗期间血浆和尿液成分变化与尿路结石复发相关的因素进行了研究。这些因素不仅受药物疗效影响，还受其他因素（血浆或尿液成分以及患者的整体健康状况等）影响。为研究药物治疗或其他治疗对血浆和尿液成分变化的影响，多元回归分析比一些研究人员使用的学生配对t检验更为合适。即使对相同的数据进行分析，这两种分析方法也会得出不同的结果。
