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[Methylprednisolone- acute spinal cord injury, benefits or risks?].

作者信息

Tęsiorowski Maciej, Potaczek Tomasz, Jasiewicz Barbara, Sapa Jacek, Zygmunt Małgorzata

机构信息

Katedra i Klinika Ortopedii i Rehabilitacji w Zakopanem Uniwersytetu Jagiellońskiego Collegium Medicum.

出版信息

Postepy Hig Med Dosw (Online). 2013 Jun 26;67:601-9. doi: 10.5604/17322693.1054873.

Abstract

Methylprednisolone is a synthetic glucocorticoid with a potent and long-acting anti-inflammatory, antiallergic and immunosuppressant. Its mechanism of action of methylprednisolone is the result of many cellular changes. Methylprednisolone is used in many diseases, such as rheumatic diseases, autoimmune diseases, allergic, anaphylactic shock, asthma. Methylprednisolone was also used in patients with spinal cord injury, in order to minimize neurological damage. While in the above mentioned fields of medicine is undeniable role of methylprednisolone, whereas its use in the treatment of traumatic spinal cord injury within the last few years raises a lot of controversy, and in most cases, the side effects of its use outweigh the potential benefits.

摘要

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