Institute of Primary Care and Public Health, School of Medicine, Cardiff University, Cardiff, UK.
Psychooncology. 2013 Nov;22(11):2576-84. doi: 10.1002/pon.3324. Epub 2013 Jun 26.
One risk management strategy that women at increased familial risk of ovarian cancer may use is screening. Until recently, this has been available as part of the UK Familial Ovarian Cancer Screening Study (UKFOCSS), using ultrasound scans of the ovaries and tumour marker blood tests. The present study aimed to gain an in-depth understanding of women's experiences of participating in ovarian cancer screening.
Semi-structured interviews were conducted with 48 UKFOCSS participants. Interviews were recorded, transcribed and relevant sections analysed using a framework approach.
Screening provided women with reassurance which they found beneficial. A sense of privilege, as well as feeling proactive in potentially detecting ovarian cancer at an early stage was described. The wider benefit to research and the potential impact this could have on others was also important to women. Negative experiences of screening included worry about the screening tests and results, false reassurance by test results and disappointment with ineffective screening. Aspects of the screening study, such as the logistics, organisation and communication, were described as both good and problematic. When weighed up by the women, most described an overall positive experience of screening.
Women reported both positive and negative experiences of screening. Overall, screening seemed to be an acceptable risk management strategy to most women who participated in this interview study. Improvements could be made particularly in helping women to understand the limitations of familial ovarian cancer screening in order to avoid false reassurance.
家族性卵巢癌风险增加的女性可能采用的风险管理策略之一是筛查。直到最近，这一直是英国家族性卵巢癌筛查研究（UKFOCSS）的一部分，该研究使用卵巢超声扫描和肿瘤标志物血液检测。本研究旨在深入了解女性参与卵巢癌筛查的体验。
对 48 名 UKFOCSS 参与者进行了半结构化访谈。对访谈进行了记录、转录，并使用框架方法对相关部分进行了分析。
筛查为女性提供了她们认为有益的安心感。她们描述了一种特权感，以及在早期检测卵巢癌方面的积极主动性。研究对女性的广泛益处以及这可能对他人产生的潜在影响也很重要。筛查的负面体验包括对筛查测试和结果的担忧、测试结果的虚假安慰以及对无效筛查的失望。筛查研究的某些方面，如后勤、组织和沟通，被描述为既有好的方面也有问题。权衡利弊后，大多数女性对筛查的总体体验表示满意。
女性报告了筛查的积极和消极体验。总的来说，对大多数参与这项访谈研究的女性来说，筛查似乎是一种可以接受的风险管理策略。可以进行改进，特别是在帮助女性理解家族性卵巢癌筛查的局限性，以避免虚假安慰。
