Joubert Kalman, Molnar Denes, Gyenis Gyula, Zsakai Annamaria
Demographic Research Institute, Hungarian Central Statistical Office , 1024 Budapest, Buday L. u. 1-3 , Hungary .
Ann Hum Biol. 2013 Sep-Oct;40(5):435-43. doi: 10.3109/03014460.2013.801511. Epub 2013 Jun 27.
Neonatal development may have an influence on post-natal nutritional status. Age at adiposity rebound is critical for later development of nutritional status.
The objective was to analyse the relationship between neonatal development and post-natal changes in nutritional status.
Subjects were studied in a longitudinal national survey (1980-2001) from birth (n = 6219) to 18.0 years (n = 1448). Subjects were divided into small (SGA), appropriate (AGA) and large for gestational age (LGA) sub-groups. Nutritional status was assessed by BMI. The Reed-Asefa model was fitted to the subject's serial data of BMI.
The body parameters of the neonatal developmental sub-groups differed significantly in all studied neonatal body dimensions: the higher the intra-uterine growth rate (the slowest growth rate was assumed in the SGA, the fastest in the LGA children), the heavier the body weight, the longer the length and the bigger the BMI values found. The nutritional status of the neonatal developmental sub-groups differed significantly during the studied post-natal interval: the higher the pre-natal growth rate, the better nutritional status (the larger BMI) was found after birth.
Neonatal development influenced strongly the post-natal nutritional status of children. The results indicate that not only age at adiposity rebound but also neonatal developmental status can be used as an indicator of later obesity.
新生儿发育可能会对出生后的营养状况产生影响。肥胖反弹的年龄对于后期营养状况的发展至关重要。
分析新生儿发育与出生后营养状况变化之间的关系。
在一项全国性纵向调查（1980 - 2001年）中对对象进行研究，从出生时（n = 6219）到18.0岁（n = 1448）。将对象分为小于胎龄儿（SGA）、适于胎龄儿（AGA）和大于胎龄儿（LGA）亚组。通过体重指数（BMI）评估营养状况。将Reed - Asefa模型应用于对象的BMI系列数据。
在所有研究的新生儿身体维度中，新生儿发育亚组的身体参数存在显著差异：宫内生长速率越高（假设SGA生长速率最慢，LGA儿童生长速率最快），体重越重，身长越长，BMI值越大。在研究的出生后时间段内，新生儿发育亚组的营养状况存在显著差异：产前生长速率越高，出生后营养状况越好（BMI越大）。
新生儿发育对儿童出生后的营养状况有强烈影响。结果表明，不仅肥胖反弹的年龄，而且新生儿发育状况都可作为后期肥胖的指标。
