Lee Jung Hwan, Lee Sang-Ho
Department of Physical Medicine and Rehabilitation, Wooridul Spine Hospital, Seoul, Korea.
Pain Med. 2013 Oct;14(10):1497-504. doi: 10.1111/pme.12180. Epub 2013 Jun 26.
Patients with lumbosacral spinal stenosis (LSS) do not always obtain satisfactory pain relief from transforaminal epidural steroid injection (TFESI) because perineural/epidural adhesions prevent the spread of injectate into the epidural space. Percutaneous adhesiolysis (PA) can eliminate the deleterious effects of adhesion. This study was to evaluate the effectiveness of PA among patients with LSS refractory to TFESI and to ascertain the prognostic factors determining PA efficacy.
Retrospective study.
Spine hospital.
Sixty-five patients with LSS refractory to TFESI who underwent PA with NaviCath® were reviewed.
We recorded Numeric Rating Scale for back pain (NRS back) and leg pain (NRS leg), and Oswestry Disability Index (ODI), at pretreatment, 2 weeks, and 3 months after treatment. Successful pain relief and functional improvement were described as a 50% and 40% or more reduction in NRS and ODI, respectively. Clinical data and radiological findings were obtained to assess the possible predictive factors for PA efficacy.
Among the 65 patients, 45 (69.2%), 40 (61.5%), and 39 (60.0%) patients showed successful outcomes in NRS back, NRS leg, and ODI at 2 weeks, respectively. Among 63 patients who were followed up at 3 months, 34 (54.0%), 32 (50.8%), and 30 (47.6%) patients showed successful results, respectively. Spondylolisthesis, previous lumbar surgery, and foraminal stenosis were associated with a significantly higher proportion of unsuccessful result in NRS and ODI (%).
PA may be a useful treatment in patients with LSS refractory to TFESI and reduce the surgical requirement. Previous surgery, spondylolisthesis, and foraminal stenosis may be associated with poor prognosis.
腰骶部椎管狭窄症(LSS)患者经椎间孔硬膜外类固醇注射(TFESI)后,疼痛缓解效果往往不尽人意,因为神经周围/硬膜外粘连会阻碍注射药物扩散至硬膜外间隙。经皮粘连松解术(PA)可消除粘连的有害影响。本研究旨在评估PA对TFESI治疗无效的LSS患者的疗效,并确定决定PA疗效的预后因素。
回顾性研究。
脊柱医院。
对65例TFESI治疗无效且接受了NaviCath®引导下PA治疗的LSS患者进行了回顾性分析。
记录患者治疗前、治疗后2周及3个月时的背痛数字评定量表(NRS背痛)、腿痛数字评定量表(NRS腿痛)及奥斯威斯功能障碍指数(ODI)。疼痛缓解成功和功能改善分别定义为NRS和ODI降低50%及以上和40%及以上。获取临床资料和影像学检查结果,以评估PA疗效的可能预测因素。
65例患者中,分别有45例(69.2%)、40例(61.5%)和39例(60.0%)在治疗后2周时NRS背痛、NRS腿痛及ODI取得成功结果。在63例接受3个月随访的患者中,分别有34例(54.0%)、32例(50.8%)和30例(47.6%)取得成功结果。椎体滑脱、既往腰椎手术及椎间孔狭窄与NRS和ODI中未成功结果的比例显著较高相关。
PA可能是TFESI治疗无效的LSS患者的一种有效治疗方法,并可减少手术需求。既往手术、椎体滑脱及椎间孔狭窄可能与预后不良相关。