估计肺中卡氏肺孢子虫负荷的半定量技术。
Semiquantitative technique for estimating Pneumocystis carinii burden in the lung.
作者信息
Baughman R P, Strohofer S, Colangelo G, Frame P T
机构信息
Department of Medicine, University of Cincinnati Medical Center, Ohio 45267-0564.
出版信息
J Clin Microbiol. 1990 Jun;28(6):1425-7. doi: 10.1128/jcm.28.6.1425-1427.1990.
Abstract
We developed a technique to estimate the amount of Pneumocystis carinii found in bronchoalveolar lavage fluid. P. carinii associated with 500 nucleated cells in the bronchoalveolar lavage fluid had little between-observer and within-observer variation. Varying the technique of the lavage did not change the amount of P. carinii recovered. This technique was used in patients treated for P. carinii pneumonia. Those patients who did not respond to treatment had more P. carinii in their bronchoalveolar lavage fluid than those who responded.
摘要
我们开发了一种技术来估计支气管肺泡灌洗（BAL）液中卡氏肺孢子虫的数量。在BAL液中，与500个有核细胞相关的卡氏肺孢子虫在观察者间和观察者内的变异很小。改变灌洗技术并不会改变回收的卡氏肺孢子虫数量。该技术用于接受卡氏肺孢子虫肺炎治疗的患者。那些对治疗无反应的患者，其BAL液中的卡氏肺孢子虫比有反应的患者更多。
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