生长板中Cdk6/Ccnd1对Rb家族蛋白的调控 - Suppr

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超能文献

Regulation of Rb family proteins by Cdk6/Ccnd1 in growth plates.

作者信息

Komori Toshihisa

出版信息

Cell Cycle. 2013 Jul 15;12(14):2161-2. doi: 10.4161/cc.25515.

DOI:10.4161/cc.25515

PMID:23803733

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3755058/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91b8/3755058/cc59648e1fa5/cc-12-2161-g1.jpg

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本文引用的文献

Oncogene. 2014 Apr 3;33(14):1862-71. doi: 10.1038/onc.2013.130. Epub 2013 Apr 29.

Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation.pRB 和 p107 的缺失会破坏软骨发育并促进软骨瘤的形成。

Oncogene. 2013 Oct;32(40):4798-805. doi: 10.1038/onc.2012.496. Epub 2012 Nov 12.

PLoS Genet. 2010 Jun 24;6(6):e1001003. doi: 10.1371/journal.pgen.1001003.

G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression.G1 细胞周期蛋白/细胞周期蛋白依赖性激酶对内源性口袋蛋白的协同磷酸化作用以不同方式调节它们与 E2F4 和 E2F1 的相互作用以及基因表达。

J Biol Chem. 2002 Dec 27;277(52):50263-74. doi: 10.1074/jbc.M209181200. Epub 2002 Oct 24.

p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development.p107和p130在软骨内骨发育过程中协同调节细胞增殖、Cbfa1表达和肥大分化。

Dev Biol. 2002 Jul 15;247(2):271-85. doi: 10.1006/dbio.2002.0691.

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.pRB以及p107/p130对于不同组E2F反应基因的调控表达是必需的。

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