Miyahara H, Imayama S, Hashizume T, Takeishi M, Hori Y, Kohda H
Department of Dermatology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
J Dermatol. 1990 May;17(5):322-5. doi: 10.1111/j.1346-8138.1990.tb01649.x.
We report two cases of pilomatrix carcinoma. Wide surgical excision, radiation, and chemotherapy were required for the first patient. The tumor eventually revealed the characteristics of a carcinoma, both clinically and histopathologically, as it recurred. In the second case, although the tumor exhibited the histology of pilomatricoma in the central part of the lesion, there were numerous outgrowing irregular nests of basaloid tumor cells with cellular atypia and frequent mitoses; these are the characteristic features of the pilomatrix carcinoma in its early stages.
我们报告两例毛母质癌。首例患者需要进行广泛手术切除、放疗和化疗。肿瘤复发时,在临床和组织病理学上最终均显示出癌的特征。在第二例中,尽管肿瘤在病变中央部分表现为毛母质瘤的组织学特征,但有许多向外生长的不规则基底样肿瘤细胞巢,伴有细胞异型性和频繁的有丝分裂;这些是毛母质癌早期阶段的特征性表现。