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接受化学预防的耳鼻喉科手术住院患者的静脉血栓栓塞症

Venous thromboembolism in otolaryngology surgical inpatients receiving chemoprophylaxis.

作者信息

Yarlagadda Bharat B, Brook Christopher D, Stein Daniel J, Jalisi Scharukh

机构信息

Department of Otolaryngology - Head and Neck Surgery, Boston Medical Center, Boston, Massachusetts.

出版信息

Head Neck. 2014 Aug;36(8):1087-93. doi: 10.1002/hed.23411. Epub 2013 Nov 27.

DOI:10.1002/hed.23411
PMID:23804491
Abstract

BACKGROUND

The Caprini risk assessment model for stratifying patients' risk for venous thromboembolism (VTE) has been validated in the otolaryngology literature. We sought to determine the incidence of VTE in patients receiving chemoprophylaxis and correlate with the Caprini risk assessment model.

METHODS

A retrospective chart review of adult surgical admissions to an academic otolaryngology service from 2007 to 2012 was performed. Caprini risk assessment model scores were calculated and compared to incidence of VTE based on diagnosis codes.

RESULTS

Seven hundred four patients met our inclusion criteria. Fifteen (2.13%) developed VTE. The Caprini risk assessment model score averaged 5.7 (range, 2-16). Patients with VTE had an average score of 9.87 versus 5.62 for those without (p < .0001). No patients with a score of 6 and below, 3.01% with 7-8, and 13.16% with a score >9 developed VTE.

CONCLUSION

The incidence of VTE increases with Caprini risk assessment model score, and a score of >8 predicts a high risk (>13%) of VTE in postoperative otolaryngology inpatients despite chemoprophylaxis.

摘要

背景

用于对患者静脉血栓栓塞(VTE)风险进行分层的Caprini风险评估模型已在耳鼻喉科文献中得到验证。我们试图确定接受化学预防的患者中VTE的发生率,并将其与Caprini风险评估模型相关联。

方法

对2007年至2012年学术性耳鼻喉科服务的成年手术入院患者进行回顾性病历审查。计算Caprini风险评估模型得分,并根据诊断代码与VTE发生率进行比较。

结果

704名患者符合我们的纳入标准。15名(2.13%)发生了VTE。Caprini风险评估模型得分平均为5.7(范围为2 - 16)。发生VTE的患者平均得分为9.87,未发生VTE的患者平均得分为5.62(p < .0001)。得分6及以下的患者中无VTE发生,7 - 8分的患者中有3.01%发生VTE,得分>9分的患者中有13.16%发生VTE。

结论

VTE的发生率随Caprini风险评估模型得分增加,得分>8分预示着术后耳鼻喉科住院患者尽管接受了化学预防,但VTE风险仍很高(>13%)。

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