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终末期肾病与肢体挽救

End-stage renal disease and limb salvage.

作者信息

Younes Houssam K, Davies Mark G, Peden Eric K

机构信息

Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas, USA.

出版信息

Methodist Debakey Cardiovasc J. 2013 Apr;9(2):108-11. doi: 10.14797/mdcj-9-2-108.

DOI:10.14797/mdcj-9-2-108
PMID:23805345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3693526/
Abstract

The prevalence of peripheral arterial disease and both traditional and nontraditional vascular risk factors are more common in patients with end-stage renal disease who are undergoing hemodialysis than the general population. Patients undergoing hemodialysis may also be at risk for peripheral arterial disease via nonvascular risk factors and the hemodialysis treatment itself. Unfortunately, because peripheral arterial disease and its risk factors in hemodialysis patients have not been thoroughly ascertained, evaluation of potential treatments has been limited. Given the high potential of morbidity and impaired quality-of-life related to peripheral arterial disease in patients with end-stage renal disease, additional studies are needed to evaluate both quality of life and potential screening for peripheral arterial disease, its risk factors, and treatments to identify areas for improvement in this vulnerable population.

摘要

与普通人群相比,正在接受血液透析的终末期肾病患者外周动脉疾病以及传统和非传统血管危险因素的患病率更高。接受血液透析的患者也可能通过非血管危险因素和血液透析治疗本身而面临外周动脉疾病的风险。不幸的是,由于尚未彻底确定血液透析患者的外周动脉疾病及其危险因素,对潜在治疗方法的评估一直很有限。鉴于终末期肾病患者外周动脉疾病导致的高发病可能性和生活质量受损,需要开展更多研究来评估生活质量以及对外周动脉疾病、其危险因素和治疗方法进行潜在筛查,以确定这一弱势群体中有待改善的领域。

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本文引用的文献

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Statins and kidney disease: is the study of heart and renal protection at the cutting edge of evidence?他汀类药物与肾脏疾病:这项研究是否处于心脏和肾脏保护证据的前沿?
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End-stage renal disease and critical limb ischemia: a deadly combination?终末期肾病和严重肢体缺血:致命组合?
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Antihypertensive treatment and stroke prevention in patients with and without chronic kidney disease: a review of controlled trials.慢性肾病患者与非慢性肾病患者的降压治疗及卒中预防:对照试验综述
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Novel and traditional cardiovascular risk factors for peripheral arterial disease in incident-dialysis patients.新发透析患者外周动脉疾病的新型及传统心血管危险因素
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Peripheral arterial disease in patients with end-stage renal disease: observations from the Dialysis Outcomes and Practice Patterns Study (DOPPS).终末期肾病患者的外周动脉疾病:来自透析结果与实践模式研究(DOPPS)的观察
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Below-the-knee angioplasty in patients with end-stage renal disease.终末期肾病患者的膝下血管成形术
J Endovasc Ther. 2005 Dec;12(6):704-13. doi: 10.1583/05-1638MR.1.