Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, 3-1 Kurumazuka, Itami, Hyogo, 664-8533, Japan.
Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University, Hidaka, Japan.
Eur J Radiol. 2014 Jan;83(1):27-31. doi: 10.1016/j.ejrad.2013.05.012. Epub 2013 Jun 24.
Honeycombing on CT is the clue for the diagnosis of usual interstitial pneumonia (UIP) and its hallmark. According to the ATS-ERS-JRS-ALAT 2010 guideline, the patients with honeycombing on CT can be diagnosed as UIP without surgical biopsy. On CT scans, it is defined as clustered cystic airspaces, typically of comparable diameters of the order of 3-10mm, which are usually subpleural and have well-defined walls. Pathologically, honeycombing consists of both collapsing of multiple fibrotic alveoli and dilation of alveolar duct and lumen Although the definition of honeycombing seems to be strict, recognition of honeycombing on CT is various among each observer Because typical honeycombing is frequently observed in the patients with UIP, we should judge clustered cysts as honeycombing when a diagnosis of UIP is suspected.
蜂巢征是寻常型间质性肺炎（UIP）诊断的线索和特征。根据 ATS-ERS-JRS-ALAT 2010 指南，如果 CT 上有蜂巢征，即使没有外科肺活检，也可以诊断为 UIP。在 CT 扫描上，它定义为簇状囊状气腔，通常直径相当，约为 3-10mm，通常位于胸膜下，边界清楚。病理上，蜂巢征既有多个纤维化肺泡的塌陷，也有肺泡管和管腔的扩张。尽管蜂巢征的定义似乎很严格，但每个观察者对 CT 上蜂巢征的识别存在差异。由于 UIP 患者常可见典型的蜂巢征，因此当怀疑 UIP 时，应将簇状囊肿判断为蜂巢征。
