Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Dev Cell. 2013 Jun 24;25(6):549-50. doi: 10.1016/j.devcel.2013.06.003.
Oligodendrocytes myelinate axons in the central nervous system (CNS). In this issue of Developmental Cell, Czopka et al. (2013) shed light on the temporal control of myelination by individual cells. They demonstrate that oligodendrocytes in vivo have only a brief time window to initiate myelination, which has important implications for CNS plasticity.
少突胶质细胞在中枢神经系统(CNS)中使轴突髓鞘化。在本期《发育细胞》中,Czopka 等人(2013)揭示了单个细胞对髓鞘形成的时间控制。他们证明,体内的少突胶质细胞只有很短的时间窗口来启动髓鞘形成,这对 CNS 的可塑性具有重要意义。