Mihaylova I, Parvanova V, Kostova P
Akush Ginekol (Sofiia). 2013;52(2):56-9.
Germ-cell tumors account for about 20% of all ovarian tumors and the dysgerminoma is the most common in this group. The treatment is surgical, followed by chemotherapy and radiotherapy in greater stage than IA. The aim of this article is to present a case report of 18-years-old patient with a left ovary dysgerminoma who had undergone a surgery--left-side ovariectomy. One year later when the patient was pregnant in 6 m.l., retroperitoneal recurrence was diagnosed by ultrasound examination. The patient has completed her pregnancy and delivered by caesarean section. Retroperitoneal recurrence of the same tumor, inoperable at this stage was histologically confirmed during the operation. The treatment continued with two courses of neoadjuvant chemotherapy followed by radical surgery with removal of the whole left kidney and the tumor. After that 2 courses of adjuvant chemotherapy were conducted, followed by prophylactic external beam radiotherapy for retroperitoneal lymph nodes. No data for local recurrences and distant metastases were found during the regular examinations, performed 2 years later. The treatment of dysgerminoma is discussed. This treatment must be complex one and should include radical surgery, chemotherapy and radiotherapy.
生殖细胞肿瘤约占所有卵巢肿瘤的20%,其中无性细胞瘤是该组中最常见的。治疗方法为手术,对于IA期以上的患者,术后还需进行化疗和放疗。本文旨在介绍一例18岁左侧卵巢无性细胞瘤患者的病例报告,该患者接受了手术——左侧卵巢切除术。一年后,患者怀孕6个月时,经超声检查诊断为腹膜后复发。患者已完成妊娠并剖宫产分娩。术中组织学证实为同一肿瘤的腹膜后复发,现阶段无法手术切除。治疗继续进行两个疗程的新辅助化疗,随后进行根治性手术,切除整个左肾和肿瘤。之后进行了两个疗程的辅助化疗,随后对腹膜后淋巴结进行预防性外照射放疗。在两年后的定期检查中未发现局部复发和远处转移的数据。本文讨论了无性细胞瘤的治疗。这种治疗必须是综合的,应包括根治性手术、化疗和放疗。