Ardoy Daniel N, Artero Enrique G, Ruiz Jonatan R, Labayen Idoia, Sjöström Michael, Castillo Manuel J, Ortega Francisco B
Department of Medical Physiology, School of Medicine, University of Granada, Granada, Spain.
Nutr Hosp. 2013 Jan-Feb;28(1):119-26. doi: 10.3305/nh.2013.28.1.6146.
Observational studies have reported an association among physical activity, fitness and lipid profile in youth. The purpose of this study was to analyse the effect of a school-based intervention focused on increasing the number and intensity of Physical Education (PE) sessions a week, on adolescents' lipid profile.
A 4-month group-randomized controlled trial was conducted in 67 adolescents (12-14 years-old) from South-East Spain, 2007. Three school classes were randomly allocated into control group (CG), experimental group-1 (EG1) and experimental group-2 (EG2). The CG received the usual PE in Spain (2 sessions/week), the EG1 received 4 PE sessions/week, and the EG2 received 4 PE sessions/week of high intensity. The main study outcomes were fasting levels of total cholesterol, high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc) and triglycerides. All the analyses were adjusted for sex, sexual maturation, attendance and baseline value of the outcome studied.
The intervention did not positively affect cardio-metabolic parameters except for LDLc, that was marginally yet significantly reduced in EG2 (-10.4 mg/dl), compared with the CG (+4.1 mg/dl) (p = 0.04); no differences were observed however for the LDLc/HDLc ratio. No significant effects were observed in EG1.
Overall, a 4-month school-based physical activity intervention did not substantially influence lipid profile in adolescents. However, the results suggest that increasing both frequency and intensity of PE sessions had a modest effect on LDLc in youth. Future studies involving larger sample sizes and longer interventions should focus on the separate effects of volume and intensity of PE.
观察性研究报告了青少年的体育活动、健康状况与血脂谱之间的关联。本研究的目的是分析一项以学校为基础的干预措施对青少年血脂谱的影响,该干预措施侧重于增加每周体育课的节数和强度。
2007年,对西班牙东南部67名12 - 14岁的青少年进行了一项为期4个月的群组随机对照试验。三个班级被随机分配到对照组(CG)、实验组1(EG1)和实验组2(EG2)。对照组接受西班牙常规体育课(每周2节),实验组1每周接受4节体育课,实验组2每周接受4节高强度体育课。主要研究结果是总胆固醇、高密度脂蛋白胆固醇(HDLc)、低密度脂蛋白胆固醇(LDLc)和甘油三酯的空腹水平。所有分析均针对性别、性成熟度、出勤率以及所研究结果的基线值进行了调整。
除LDLc外,该干预对心血管代谢参数没有积极影响。与对照组(+4.1mg/dl)相比,实验组2的LDLc略有但显著降低(-10.4mg/dl)(p = 0.04);然而,LDLc/HDLc比值未观察到差异。实验组1未观察到显著影响。
总体而言,一项为期4个月的以学校为基础的体育活动干预对青少年血脂谱没有实质性影响。然而,结果表明,增加体育课的频率和强度对青少年的LDLc有适度影响。未来涉及更大样本量和更长干预时间的研究应关注体育课的量和强度的单独影响。