* Comprehensive Hearing Center (CHC), Department of Otorhinolaryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius Maximilian-University Hospitals , Würzburg , Germany.
Int J Audiol. 2013 Oct;52(10):698-705. doi: 10.3109/14992027.2013.804634. Epub 2013 Jun 28.
The present paper reports the results of a study on a group of newborns whose chirp-evoked auditory brainstem responses (ABR) were recorded at different repetition rates. The study was aimed at finding an optimum repetition rate for the chirp stimulus that facilitates a short response detection time in the frequency domain.
Chirp-evoked ABR were recorded at six different stimulation rates between 20/s and 100/s. The stimulation level was 35 dB nHL. The mean harmonic related SNR was calculated, and the response detection time and rate were assessed using a detection algorithm.
A group of 80 sleeping and 27 awake newborns with normal hearing were included.
The highest mean harmonic-related SNR in both groups was found at 60/s. The signal-to-noise ratio (SNR) was significantly smaller for the awake newborns. A significantly shorter detection time can be achieved for both newborn groups at 60/s compared to the other rates tested. Response detection in the group of awake newborns profited more from the change to 60/s compared to the sleeping newborns.
It can be expected that with this optimized stimulus paradigm a shorter test time and a higher specificity of the hearing screening can be reached.
本研究报告了一组新生儿的啁啾诱发听觉脑干反应(ABR)在不同重复率下的记录结果。该研究旨在找到一种优化的啁啾刺激重复率,以在频域中实现短的响应检测时间。
在 20/s 至 100/s 之间的六个不同刺激率下记录啁啾诱发 ABR。刺激水平为 35dB nHL。计算平均谐波相关信噪比,并使用检测算法评估响应检测时间和速率。
包括 80 名睡眠和 27 名清醒且听力正常的新生儿。
两组中最高的平均谐波相关 SNR 均在 60/s 时出现。清醒新生儿的信噪比明显较小。与测试的其他速率相比,两组新生儿在 60/s 时都可以实现更短的检测时间。与睡眠新生儿相比,清醒新生儿的反应检测从转换到 60/s 中获益更多。
可以预期,通过这种优化的刺激范式,可以缩短测试时间并提高听力筛查的特异性。