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人在进行握力和肌肉缺血时,压力反射节律仍然存在。

Human baroreflex rhythms persist during handgrip and muscle ischaemia.

机构信息

Department of Medicine and Physiology, Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Richmond, VA, USA; Medical College of Virginia at Virginia Commonwealth University, Richmond, VA, USA.

出版信息

Acta Physiol (Oxf). 2013 Oct;209(2):114-23. doi: 10.1111/apha.12143. Epub 2013 Jul 25.

Abstract

AIM

To determine whether physiological, rhythmic fluctuations of vagal baroreflex gain persist during exercise, post-exercise ischaemia and recovery.

METHODS

We studied responses of six supine healthy men and one woman to a stereotyped protocol comprising rest, handgrip exercise at 40% maximum capacity to exhaustion, post-exercise forearm ischaemia and recovery. We measured electrocardiographic R-R intervals, photoplethysmographic finger arterial pressures and peroneal nerve muscle sympathetic activity. We derived vagal baroreflex gains from a sliding (25-s window moved by 2-s steps) systolic pressure-R-R interval transfer function at 0.04-0.15 Hz.

RESULTS

Vagal baroreflex gain oscillated at low, nearly constant frequencies throughout the protocol (at approx. 0.06 Hz - a period of about 18 s); however, during exercise, most oscillations were at low-gain levels, and during ischaemia and recovery, most oscillations were at high-gain levels.

CONCLUSIONS

Vagal baroreflex rhythms are not abolished by exercise, and they are not overwhelmed after exercise during ischaemia and recovery.

摘要

目的

确定在运动、运动后缺血和恢复期间,迷走神经压力反射增益的生理、有节奏的波动是否持续。

方法

我们研究了 6 名仰卧健康男性和 1 名女性对标准化方案的反应,该方案包括休息、以最大容量的 40%进行握力运动直至力竭、运动后前臂缺血和恢复。我们测量了心电图 R-R 间隔、光体积描记手指动脉血压和腓肠神经肌肉交感神经活动。我们从 0.04-0.15 Hz 的收缩压-R-R 间隔传递函数的滑动(25 秒窗口以 2 秒步长移动)中得出迷走神经压力反射增益。

结果

在整个方案中,迷走神经压力反射增益以低、几乎恒定的频率振荡(约 0.06 Hz-周期约 18 秒);然而,在运动期间,大多数振荡处于低增益水平,而在缺血和恢复期间,大多数振荡处于高增益水平。

结论

迷走神经压力反射节律不因运动而消除,并且在运动后缺血和恢复期间不会被淹没。

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