Division of General Internal Medicine, University of Washington School of Medicine, 4245 Roosevelt Way Northeast, Seattle, WA 98115, USA.
Med Clin North Am. 2013 Jul;97(4):581-600, x. doi: 10.1016/j.mcna.2013.03.002.
Recipients of solid organ transplants (SOT) need primary care providers (PCPs) who are familiar with their unique needs and understand the lifelong infectious risks faced by SOT patients because of their need for lifelong immunosuppressive medications. SOT recipients can present with atypical and muted manifestations of infections, for which the knowledgable PCP will initiate a comprehensive evaluation. The goal of this article is to familiarize PCPs with the infectious challenges facing SOT patients. General concepts are reviewed, and a series of patient cases described that illustrate the specific learning points based on common presenting clinical symptoms.
实体器官移植受者(SOT)需要初级保健提供者(PCP),他们熟悉受者的独特需求,并了解 SOT 患者因需要终身免疫抑制药物而面临的终身感染风险。SOT 受者可能会出现感染的非典型和不明显表现,对此,有经验的 PCP 将启动全面评估。本文的目的是使 PCP 熟悉 SOT 患者面临的感染挑战。本文回顾了一般概念,并描述了一系列患者病例,根据常见的临床表现说明了具体的学习要点。