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患有内脏肥大细胞瘤和嗜酸性粒细胞增多症的犬的吕弗勒心内膜炎和双腔嗜酸性粒细胞性积液

Loeffler's endocarditis and bicavity eosinophilic effusions in a dog with visceral mast cell tumour and hypereosinophilia.

作者信息

Harris B J, Constantino-Casas F, Archer J, Herrtage M E

机构信息

Northwest Surgeons, Delamere House, Ashville Point, Sutton Weaver, Cheshire WA7 3FW, UK.

出版信息

J Comp Pathol. 2013 Nov;149(4):429-33. doi: 10.1016/j.jcpa.2013.04.005. Epub 2013 Jun 25.

DOI:10.1016/j.jcpa.2013.04.005
PMID:23809908
Abstract

A 9-year-old crossbred dog was presented with a 2-week history of diarrhoea and tachypnoea. Marked circulating eosinophilia was identified. Pleural and abdominal effusions were detected by radiography and ultrasonography and cytological examination of these fluids revealed a predominance of eosinophils. Splenic and hepatic cytology revealed mast cell neoplasia, which was confirmed as visceral mast cell tumour on post-mortem examination. Histological changes of myocardial inflammation, necrosis and fibrosis were found. These findings are consistent with Loeffler's endocarditis.

摘要

一只9岁的杂种犬出现了为期2周的腹泻和呼吸急促症状。发现有明显的循环嗜酸性粒细胞增多。通过X线摄影和超声检查发现胸腔和腹腔积液,对这些液体进行细胞学检查显示嗜酸性粒细胞占优势。脾脏和肝脏细胞学检查发现肥大细胞瘤,死后检查证实为内脏肥大细胞肿瘤。发现心肌有炎症、坏死和纤维化的组织学变化。这些发现与吕弗勒心内膜炎相符。

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