Grønning Helene, Kristiansen Susanne, Dyre Dorte, Rahmani Abdul, Gyllenborg Jesper, Høgh Peter
Department of Neurology, Roskilde Hospital.
Dan Med J. 2013 Jul;60(7):A4649.
The purpose of the study was to analyse caregiver burden and consumption of psychosocial services in a consecutive group of patients with early onset Alzheimer's disease (EOAD) compared with a matching group with late onset Alzheimer's disease (LOAD).
This was a case-control study with 42 patients who were matched according to disease severity at the time of diagnosis. Caregivers in both groups were interviewed using the Neuro Psychiatric Inventory (NPI), the Activities of Daily Living (ADL) scale and the Resource Utilization in Dementia scale. The quantitative outcomes were compared statistically.
The EOAD group had a significantly higher ADL score than the LOAD group. There was a trend towards caregivers in the LOAD group spending more time helping the patients, and they needed more social services than the EOAD group. NPI scores were not significantly different, but a tendency towards a higher caregiver burden in the EOAD group was observed.
The higher caregiver burden in patients with EOAD--despite a better ADL function than LOAD patients--suggests that the existing psychosocial services might be particularly insufficient for caregivers in EOAD.
The study was funded by a three-month scholarship grant from the research fund at Roskilde Hospital.
not relevant.
本研究旨在分析一组连续的早发性阿尔茨海默病（EOAD）患者与一组匹配的晚发性阿尔茨海默病（LOAD）患者的照料者负担及心理社会服务的使用情况。
这是一项病例对照研究，纳入了42例患者，这些患者在诊断时根据疾病严重程度进行了匹配。两组的照料者均使用神经精神科问卷（NPI）、日常生活活动（ADL）量表和痴呆症资源利用量表进行访谈。对定量结果进行了统计学比较。
EOAD组的ADL评分显著高于LOAD组。LOAD组的照料者有花费更多时间帮助患者的趋势，且他们比EOAD组需要更多的社会服务。NPI评分无显著差异，但观察到EOAD组照料者负担有加重的趋势。
尽管EOAD患者的ADL功能比LOAD患者更好，但EOAD患者的照料者负担更重，这表明现有的心理社会服务可能对EOAD患者的照料者尤其不足。
本研究由罗斯基勒医院研究基金提供的为期三个月的奖学金资助。
不相关。
