癌症概念和原则：介入肿瘤学家入门指南-第二部分。
Cancer concepts and principles: primer for the interventional oncologist-part II.
机构信息
Department of Radiology and Division of Interventional Oncology, Northwestern University, Chicago, IL 60611, USA.
出版信息
J Vasc Interv Radiol. 2013 Aug;24(8):1167-88. doi: 10.1016/j.jvir.2013.04.023. Epub 2013 Jun 28.
Abstract
This is the second of a two-part overview of the fundamentals of oncology for interventional radiologists. The first part focused on clinical trials, basic statistics, assessment of response, and overall concepts in oncology. This second part aims to review the methods of tumor characterization; principles of the oncology specialties, including medical, surgical, radiation, and interventional oncology; and current treatment paradigms for the most common cancers encountered in interventional oncology, along with the levels of evidence that guide these treatments.
摘要
这是介入放射学家肿瘤学基础知识两部分内容概述中的第二部分。第一部分重点介绍临床试验、基础统计学、反应评估和肿瘤学的总体概念。第二部分旨在回顾肿瘤特征化的方法；肿瘤学专业的原则，包括医学、外科学、放射学和介入肿瘤学；以及介入肿瘤学中最常见癌症的当前治疗模式，以及指导这些治疗的证据水平。
相似文献
1
Cancer concepts and principles: primer for the interventional oncologist-part II.癌症概念和原则：介入肿瘤学家入门指南-第二部分。
J Vasc Interv Radiol. 2013 Aug;24(8):1167-88. doi: 10.1016/j.jvir.2013.04.023. Epub 2013 Jun 28.
2
Cancer concepts and principles: primer for the interventional oncologist-part I.癌症概念和原则：介入肿瘤学家入门-第一部分。
J Vasc Interv Radiol. 2013 Aug;24(8):1157-64. doi: 10.1016/j.jvir.2013.04.024. Epub 2013 Jun 25.
3
Transarterial chemoembolization with irinotecan beads in the treatment of colorectal liver metastases: systematic review.经动脉化疗栓塞术联合伊立替康微球治疗结直肠癌肝转移：系统评价。
J Vasc Interv Radiol. 2013 Aug;24(8):1209-17. doi: 10.1016/j.jvir.2013.05.055.
4
Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.奥沙利铂联合 5-氟尿嘧啶和亚叶酸在晚期结直肠癌一线和二线治疗中的作用。
Curr Oncol. 2006 Oct;13(5):173-84. doi: 10.3747/co.v13i5.99.
5
Randomized controlled trial of irinotecan drug-eluting beads with simultaneous FOLFOX and bevacizumab for patients with unresectable colorectal liver-limited metastasis.随机对照试验研究伊立替康载药微球联合 FOLFOX 和贝伐珠单抗治疗不可切除结直肠癌肝转移患者
Cancer. 2015 Oct 15;121(20):3649-58. doi: 10.1002/cncr.29534. Epub 2015 Jul 6.
6
Irinotecan drug-eluting beads in the treatment of chemo-naive unresectable colorectal liver metastasis with concomitant systemic fluorouracil and oxaliplatin: results of pharmacokinetics and phase I trial.伊立替康载药微球治疗同期全身氟尿嘧啶和奥沙利铂化疗的初治不可切除结直肠癌肝转移：药代动力学和 I 期临床试验结果。
J Gastrointest Surg. 2012 Aug;16(8):1531-8. doi: 10.1007/s11605-012-1892-8. Epub 2012 Apr 24.
7
Evidence-based medical oncology and interventional radiology paradigms for liver-dominant colorectal cancer metastases.以证据为基础的肝转移为主的结直肠癌的医学肿瘤学和介入放射学模式
World J Gastroenterol. 2016 Mar 21;22(11):3127-49. doi: 10.3748/wjg.v22.i11.3127.
8
Barriers to drug delivery in interventional oncology.介入肿瘤学中的药物递释障碍。
J Vasc Interv Radiol. 2013 Aug;24(8):1201-7. doi: 10.1016/j.jvir.2013.03.034. Epub 2013 Jun 2.
9
Bevacizumab plus FOLFIRI or FOLFOX as third-line or later treatment in patients with metastatic colorectal cancer after failure of 5-fluorouracil, irinotecan, and oxaliplatin: a retrospective analysis.贝伐单抗联合FOLFIRI或FOLFOX作为氟尿嘧啶、伊立替康和奥沙利铂治疗失败后转移性结直肠癌患者的三线或后续治疗：一项回顾性分析
Med Oncol. 2009;26(1):32-7. doi: 10.1007/s12032-008-9077-8. Epub 2008 May 22.
10
Bevacizumab in combination with irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) in patients with metastatic colorectal cancer who were previously treated with oxaliplatin-containing regimens: a multicenter observational cohort study (TCTG 2nd-BV study).贝伐珠单抗联合伊立替康、5-氟尿嘧啶和亚叶酸（FOLFIRI）治疗既往含奥沙利铂方案治疗的转移性结直肠癌患者：一项多中心观察性队列研究（TCTG 2 期-BV 研究）。
Med Oncol. 2012 Dec;29(4):2842-8. doi: 10.1007/s12032-011-0151-2. Epub 2011 Dec 31.
引用本文的文献
1
Introduction to interventional oncology: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.介入肿瘤学概论：COG 诊断成像委员会/SPR 肿瘤学委员会白皮书。
Pediatr Blood Cancer. 2023 Jun;70 Suppl 4(Suppl 4):e30234. doi: 10.1002/pbc.30234. Epub 2023 Feb 22.
2
Precision Imaging Guidance in the Era of Precision Oncology: An Update of Imaging Tools for Interventional Procedures.精准肿瘤学时代的精准成像引导：介入手术成像工具的最新进展
J Clin Med. 2022 Jul 12;11(14):4028. doi: 10.3390/jcm11144028.
3
Cancer Biology, Epidemiology, and Treatment in the 21st Century: Current Status and Future Challenges From a Biomedical Perspective.二十一世纪的癌症生物学、流行病学和治疗：从生物医学角度看现状和未来挑战。
Cancer Control. 2021 Jan-Dec;28:10732748211038735. doi: 10.1177/10732748211038735.
4
Role of interventional radiology in managing pediatric liver tumors : Part 2: percutaneous interventions.介入放射学在小儿肝脏肿瘤治疗中的作用：第2部分：经皮介入治疗
Pediatr Radiol. 2018 Apr;48(4):565-580. doi: 10.1007/s00247-018-4072-5. Epub 2018 Feb 2.
5
Role of interventional radiology in managing pediatric liver tumors : Part 1: Endovascular interventions.介入放射学在小儿肝脏肿瘤治疗中的作用：第1部分：血管内介入治疗
Pediatr Radiol. 2018 Apr;48(4):555-564. doi: 10.1007/s00247-018-4068-1. Epub 2018 Jan 23.
6
Cross-sectional study of the provision of interventional oncology services in the UK.英国介入肿瘤学服务提供情况的横断面研究。
BMJ Open. 2017 Oct 22;7(10):e016631. doi: 10.1136/bmjopen-2017-016631.
7
Interventional Oncology Service Development.介入肿瘤学服务发展
Semin Intervent Radiol. 2017 Jun;34(2):182-186. doi: 10.1055/s-0037-1601853. Epub 2017 Jun 1.
8
Transarterial approaches to primary and secondary hepatic malignancies.经动脉途径治疗肝脏原发和继发恶性肿瘤。
Nat Rev Clin Oncol. 2015 Aug;12(8):481-9. doi: 10.1038/nrclinonc.2015.78. Epub 2015 May 19.
9
Synthesis and biological evaluation of panitumumab-IRDye800 conjugate as a fluorescence imaging probe for EGFR-expressing cancers.帕尼单抗-IRDye800偶联物作为用于表达表皮生长因子受体（EGFR）癌症的荧光成像探针的合成及生物学评价
Medchemcomm. 2014 Sep;5(9):1337-1346. doi: 10.1039/C4MD00116H.
本文引用的文献
1
The evolving role of partial breast irradiation in early-stage breast cancer.早期乳腺癌中部分乳房照射的作用演变。
Ann Surg Oncol. 2013 Aug;20(8):2534-40. doi: 10.1245/s10434-013-2923-8. Epub 2013 Mar 6.
2
New pathologic classification of lung cancer: relevance for clinical practice and clinical trials.肺癌的新病理分类：对临床实践和临床试验的意义。
J Clin Oncol. 2013 Mar 10;31(8):992-1001. doi: 10.1200/JCO.2012.46.9270. Epub 2013 Feb 11.
3
Is less than 5 mm as the narrowest surgical margin width in central resections of hepatocellular carcinoma justified?肝癌中央切除术的手术切缘最小宽度是否应小于 5mm？
Am J Surg. 2013 Jul;206(1):64-71. doi: 10.1016/j.amjsurg.2012.06.010. Epub 2013 Feb 4.
4
Percutaneous ablation of renal masses measuring 3.0 cm and smaller: comparative local control and complications after radiofrequency ablation and cryoablation.经皮消融直径 3.0cm 及以下的肾肿瘤：射频消融与冷冻消融后的局部控制与并发症比较。
AJR Am J Roentgenol. 2013 Feb;200(2):461-6. doi: 10.2214/AJR.12.8618.
5
Pulmonary metastasectomy for sarcoma of gynaecologic origin.妇科来源肉瘤的肺转移切除术。
Heart Lung Circ. 2013 Apr;22(4):270-5. doi: 10.1016/j.hlc.2012.11.001. Epub 2012 Dec 21.
6
Advances in radiotherapy.放射治疗的进展
BMJ. 2012 Dec 4;345:e7765. doi: 10.1136/bmj.e7765.
7
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial.regorafenib 治疗伊马替尼和舒尼替尼治疗失败的晚期胃肠道间质瘤的疗效和安全性（GRID）：一项国际、多中心、随机、安慰剂对照、3 期临床试验。
Lancet. 2013 Jan 26;381(9863):295-302. doi: 10.1016/S0140-6736(12)61857-1. Epub 2012 Nov 22.
8
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial.regorafenib 单药治疗既往治疗的转移性结直肠癌（CORRECT）：一项国际、多中心、随机、安慰剂对照、3 期临床试验。
Lancet. 2013 Jan 26;381(9863):303-12. doi: 10.1016/S0140-6736(12)61900-X. Epub 2012 Nov 22.
9
Enhancement of tumor-associated antigen-specific T cell responses by radiofrequency ablation of hepatocellular carcinoma.射频消融肝癌增强肿瘤相关抗原特异性 T 细胞反应。
Hepatology. 2013 Apr;57(4):1448-57. doi: 10.1002/hep.26153.
10
Pulmonary metastasectomy for sarcoma: a systematic review of reported outcomes in the context of Thames Cancer Registry data.肉瘤肺转移切除术：基于 Thames 癌症登记处数据的报告结果的系统回顾。
BMJ Open. 2012 Oct 8;2(5). doi: 10.1136/bmjopen-2012-001736. Print 2012.
Zotero 插件