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马来西亚吉兰丹州一家三级教学医院的粪类圆线虫感染患者回顾。

Review of patients with Strongyloides stercoralis infestation in a tertiary teaching hospital, Kelantan.

作者信息

Azira N M S, Abdel Rahman M Z, Zeehaida M

机构信息

Universiti Teknologi Mara, Cluster of Pathology and Laboratory Medicine, Selangor, Malaysia.

出版信息

Malays J Pathol. 2013 Jun;35(1):71-6.

PMID:23817397
Abstract

Strongyloides stercoralis is an intestinal nematode infecting humans. The actual prevalence of infestation with this parasite in our setting is not well established. Thus, this study was conducted to determine the age, sex and co-morbid conditions among patients with S. stercoralis infestation as well as to study the common manifestations of strongyloidiasis in our patients. Records of patients with positive S. stercoralis larvae from January 2000 to December 2012 in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan were reviewed. Ten patients were male and two were female. Their ages ranged from 19 to 78 years old. The majority (92%) of cases, presented with intestinal symptoms and 50% with moderate to severe anaemia. Thirty percent of cases had extraintestinal manifestations such as cough, sepsis and pleural effusion. Ninety-two percent of the patients had a comorbid illness. Most patients were immunocompromised, with underlying diabetes mellitus, retroviral disease, lymphoma and steroid therapy contributing to about 58% of cases. Only 58% were treated with anti-helminthic drugs. Strongyloidiasis is present in our local setting, though the prevalence could be underestimated.

摘要

粪类圆线虫是一种感染人类的肠道线虫。在我们所处环境中,这种寄生虫感染的实际流行情况尚未明确。因此,开展本研究以确定粪类圆线虫感染患者的年龄、性别和合并症情况,并研究我们的患者中类圆线虫病的常见表现。回顾了2000年1月至2012年12月在马来西亚理科大学医院(位于吉兰丹州瓜拉基里安)粪类圆线虫幼虫检测呈阳性的患者记录。10例患者为男性,2例为女性。他们的年龄在19岁至78岁之间。大多数病例(92%)出现肠道症状,50%伴有中度至重度贫血。30%的病例有肠道外表现,如咳嗽、败血症和胸腔积液。92%的患者有合并症。大多数患者免疫功能低下,潜在的糖尿病、逆转录病毒病、淋巴瘤和类固醇治疗约占病例的58%。只有58%的患者接受了抗蠕虫药物治疗。我们当地存在类圆线虫病,尽管其患病率可能被低估。

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